What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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1 A systematic framework to classify the status of research on spinal cord injury and physical activity Archives of Physical Medicine and Rehabilitation, May 16, 2013 Clinical Article
2 Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults Cochrane Reviews, May 14, 2013 Evidence Based Medicine Clinical Article
3 Hypoxic Preconditioning with Cobalt of Bone Marrow Mesenchymal Stem Cells Improves Cell Migration and Enhances Therapy for Treatment of Ischemic Acute Kidney Injury PLOS ONE, May 13, 2013 Review Article
4 Safety and efficacy of vernakalant for acute cardioversion of atrial fibrillation: an update Full Text Vascular Health and Risk Management, May 10, 2013 Clinical Article
5 Thrombocytopenia as a mortality risk factor in acute respiratory failure in H1N1 influenza Full Text Swiss Medical Weekly, May 9, 2013 Clinical Article
6 Behavioral pain assessment tool for critically ill adults unable to self-report pain American Journal of Critical Care, May 9, 2013 Clinical Article
7 Recognizing and managing hereditary angioedema Full Text Cleveland Clinic Journal of Medicine, May 8, 2013
8 Effects of an Acute Care for Elders Unit on Costs and 30-Day Readmissions ACE Unit Model for Care JAMA Internal Medicine, May 7, 2013 Evidence Based Medicine Clinical Article
9 Evaluation of the Mobile Acute Care of the Elderly (MACE) Service JAMA Internal Medicine, May 7, 2013 Evidence Based Medicine
10 Serum microRNAs profile from genom-wide serves as a fingerprint for diagnosis of acute myocardial infarction and angina pectoris Full Text BMC Genomics, May 6, 2013 Clinical Article
11 New insights of P2X7 receptor signaling pathway in alveolar functions Full Text Journal of Biomedical Science, May 6, 2013
12 Intensive care pain treatment and sedation: Nurses' experiences of the conflict between clinical judgement and standardised care: An explorative study Intensive and Critical Care Nursing, May 3, 2013 Clinical Article
13
Does music influence stress in mechanically ventilated patients?
Intensive and Critical Care Nursing, May 3, 2013
Clinical Article
Exclusive Author Commentary
14 Influence of neighborhood household income on early death or urgent hospital readmission Journal of Hospital Medicine, May 1, 2013 Review Article
15 EHRA Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation: executive summary European Heart Journal, April 30, 2013 Clinical Guideline Clinical Article
16 Predictors of 30-day mortality and outcome in cases of myocardial infarction with cardiogenic shock treated by extracorporeal life support European Journal of Cardio-Thoracic Surgery, April 29, 2013 Clinical Article
17 A New Decline in Hospitalization with Atrial Fibrillation among the Elderly American Journal of Medicine, April 26, 2013 Evidence Based Medicine
18 A Physical Therapist-Established Intensive Care Unit Early Mobilization Program: A Quality Improvement Project for Critical Care at the University of California San Francisco Medical Center Physical Therapy, April 24, 2013 Review Article
19 Incidence and Factors Associated With Falls in Independent Ambulatory Individuals With Spinal Cord Injury: A 6-Month Prospective Study Physical Therapy, April 24, 2013 Clinical Article
20 Should all acutely ill medical patients be treated with antithrombotic drugs? Full Text Thrombosis and Haemostasis, April 23, 2013 Review Article
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 Head impact biomechanics in ski related accident British Journal of Sports Medicine, April 9, 2013
2 Should all acutely ill medical patients be treated with antithrombotic drugs? Thrombosis and Haemostasis, April 23, 2013 Free full text Review Article
3 Invasive mechanical ventilation in acute coronary syndromes in the era of percutaneous coronary intervention European Heart Journal: Acute Cardiovascular Care, April 16, 2013
4 De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock Cochrane Reviews, April 11, 2013 Review Article
5 Development of a checklist of safe discharge practices for hospital patients Journal of Hospital Medicine, April 18, 2013
6 Calcium antagonists as an add-on therapy for drug-resistant epilepsy Cochrane Reviews, April 2, 2013 Review Article
7 Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections Cochrane Reviews, March 29, 2013 Review Article
8 Single dose oral ibuprofen plus codeine for acute postoperative pain in adults Cochrane Reviews, April 1, 2013 Review Article
9 A Physical Therapist-Established Intensive Care Unit Early Mobilization Program: A Quality Improvement Project for Critical Care at the University of California San Francisco Medical Center Physical Therapy, April 24, 2013 Review Article
10 Proton Pump Inhibitors and Risk of 1-Year Mortality and Rehospitalization in Older Patients Discharged From Acute Care Hospitals Proton Pump Inhibitors in Older Patients JAMA Internal Medicine, April 10, 2013
11 State of the evidence: mechanical ventilation with PEEP in patients with cardiogenic shock Heart, April 15, 2013
12 Pulmonary-renal syndrome: a life threatening but treatable condition Postgraduate Medical Journal, February 26, 2013 Evidence Based Medicine
13 Ultrasound imaging for lumbar punctures and epidural catheterisations: systematic review and meta-analysis British Medical Journal, April 10, 2013 Free full text Evidence Based Medicine Review Article
14 Application of appropriateness criteria for hospitalization in COPD exacerbation Internal and Emergency Medicine, April 5, 2013
15 Septic shock: The initial moments and beyond Cleveland Clinic Journal of Medicine, March 5, 2013 Free full text Review Article
16 Fluoxetine for motor recovery after acute intracerebral hemorrhage (FMRICH): study protocol for a randomized, double-blind, placebo-controlled, multicenter trial Trials, April 5, 2013 Free full text
17 Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial The Lancet, March 26, 2013
18 Rivaroxaban for Thromboprophylaxis in Acutely Ill Medical Patients New England Journal of Medicine, March 15, 2013
19 Identification of patients with low-risk pulmonary embolism suitable for outpatient treatment using the pulmonary embolism severity index (PESI) Irish Journal of Medical Science, March 26, 2013
20 Diagnosing tuberculous meningitis ? have we made any progress? Tropical Medicine & International Health, March 27, 2013 Review Article
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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