What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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21 Nature as a source of metabolites with cholinesterase-inhibitory activity: an approach to Alzheimers disease treatment Journal of Pharmacy and Pharmacology, May 21, 2013 Clinical Article
22 Prevalence of complementary and alternative medicine use in a community-based population in South Korea: A systematic review Complementary Therapies in Medicine, May 21, 2013 Evidence Based Medicine Review Article
23 Filling the gap between traditional Chinese medicine and modern medicine, are we heading to the right direction? Complementary Therapies in Medicine, May 21, 2013 Clinical Article
24 Effect of a steam foot spa on geriatric inpatients with cognitive impairment: a pilot study Full Text Clinical Interventions in Aging, May 20, 2013 Review Article
25 Chinese Herbal Formula Huo-Luo-Xiao-Ling Dan Protects against Bone Damage in Adjuvant Arthritis by Modulating the Mediators of Bone Remodeling Full Text Evidence-based Complementary and Alternative Medicine , May 17, 2013 Clinical Article
26 Puerarin stimulates proliferation and differentiation and protects against cell death in human osteoblastic MG-63 cells via ER-dependent MEK/ERK and PI3K/Akt activation Phytomedicine, May 16, 2013 Review Article
27 Acupuncture in Preventing Postoperative Nausea and Vomiting: Efficacy of Two Acupuncture Points Versus a Single One Full Text Journal of Acupuncture and Meridian Studies, May 16, 2013 Clinical Article
28 Pursuit of Complementary and Alternative Medicine Treatments in Adolescents With Cerebral Palsy Journal of Child Neurology, May 15, 2013 Review Article
29 Herbal preparations for uterine fibroids Cochrane Reviews, May 14, 2013 Evidence Based Medicine Clinical Article
30 Comparison Between the Efficacy of Ginger and Sumatriptan in the Ablative Treatment of the Common Migraine Phytotherapy Research, May 14, 2013 Review Article
31 Therapeutic efficacy of the Qing Dai in patients with intractable ulcerative colitis Full Text World Journal of Gastroenterology, May 14, 2013 Review Article
32 Antiplasmodial activity of sesquiterpene lactones and a sucrose ester from Vernonia guineensis Benth. (Asteraceae) Journal of Ethnopharmacology , May 14, 2013 Review Article
33 Is Integrative Medicine the Next New Frontier in Medicine? Clinical Reviews in Allergy and Immunology, May 14, 2013 Review Article
34 The Effectiveness of Acupressure for the Control and Management of Chemotherapy-Related Acute and Delayed Nausea: A Randomized Controlled Trial Journal of Pain and Symptom Management, May 13, 2013 Clinical Article
35 Efficacy of individualized homeopathic treatment and fluoxetine for moderate to severe depression in peri- and postmenopausal women (HOMDEP-MENOP): study protocol for a randomized, double-dummy, double-blind, placebo-controlled trial Full Text Trials, May 10, 2013 Clinical Article
36 Comparing the effects of individualized, standard, sham and no acupuncture in the treatment of knee osteoarthritis: a multicenter randomized controlled trial Full Text Trials, May 10, 2013 Clinical Article
37 Antibacterial activities of almond skins on cagA-positive and-negative clinical isolates of Helicobacter pylori Full Text BMC Microbiology, May 10, 2013 Clinical Article
38 Direct Moxibustion to Treat Spleen Qi and Yang Deficiency Fatigue: A Pilot Study Full Text Journal of Acupuncture and Meridian Studies, May 10, 2013 Clinical Article
39 Vitamin D and systemic lupus erythematosus: an update Expert Review of Clinical Immunology, May 9, 2013 Review Article
40 A phase II randomised double-blind placebo-controlled clinical trial investigating the efficacy and safety of ProstateEZE Max: A herbal medicine preparation for the management of symptoms of benign prostatic hypertrophy Complementary Therapies in Medicine, May 9, 2013 Clinical Article
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summaryIndexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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