Internal Medicine - Rheumatology News & Articles

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Articles

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1 Chinese Herbal Formula Huo-Luo-Xiao-Ling Dan Protects against Bone Damage in Adjuvant Arthritis by Modulating the Mediators of Bone Remodeling Full Text Evidence-based Complementary and Alternative Medicine , May 17, 2013 Clinical Article

2 Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of Systemic Sclerosis and Sjogren’s Syndrome Autoimmunity Reviews, May 17, 2013 Clinical Article

3 Lung Involvement in Connective Tissue Diseases: A Comprehensive Review and A Focus On Rheumatoid Arthritis Autoimmunity Reviews, May 17, 2013 Clinical Article

4 Current Status of Implementation of Self-Administration Training in Various Regions of Europe, Canada and the USA in the Management of Hereditary Angioedema International Archives of Allergy and Immunology, May 17, 2013 Clinical Article

5 Recent Advances in Hereditary Angioedema Self-Administration Treatment: Summary of an International Hereditary Angioedema Expert Meeting International Archives of Allergy and Immunology, May 17, 2013 Review Article

6 Validation of an Adapted Arabic Version of Fibromyalgia Syndrome Impact Questionnaire Rheumatology International, May 17, 2013 Clinical Article

7 Plasma nitrite levels, total antioxidant status, total oxidant status, and oxidative stress index in patients with tension-type headache and fibromyalgia Clinical Neurology and Neurosurgery, May 17, 2013 Clinical Article

8 Psychometric analysis of measuring functional outcomes in tibial plateau fractures using the Short Form 36 (SF-36), Short Musculoskeletal Function Assessment (SMFA) and the Western Ontario McMaster Osteoarthritis (WOMAC) questionnaires Injury, May 17, 2013 Clinical Article

9 Prioritizing the patient: optimizing therapy in rheumatoid arthritis. Results of a patient questionnaire in northern Germany Full Text Open Access Rheumatology: Research and Reviews, May 17, 2013 Clinical Article

Prior Articles

10 Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial The Lancet, May 16, 2013 Clinical Article

11 Anterior Chest Wall Pain in Recent Inflammatory Back Pain Suggestive of Spondyloarthritis. Data from the DESIR Cohort The Journal of Rheumatology, May 16, 2013 Clinical Article

12 Greater intake of fruit and vegetables is associated with a lower risk of osteoporotic hip fractures in elderly Chinese: a 1:1 matched case-control study Osteoporosis International, May 16, 2013 Clinical Article

13 Golimumab in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: Results Through 2 Years of the GO-FORWARD Study Extension The Journal of Rheumatology, May 16, 2013 Clinical Article

14 Incidence of Spondyloarthropathy in Patients with Ulcerative Colitis: A Population-based Study The Journal of Rheumatology, May 16, 2013 Clinical Article

15 Angiogenesis in rheumatoid arthritis is directly fostered by TLR5 ligation and indirectly through IL-17 induction Arthritis & Rheumatism, May 16, 2013 Review Article

16 Hsp90 inhibition protect against biomechanically-induced osteoarthritis Arthritis & Rheumatism, May 16, 2013 Review Article

17 Expression of cathepsin K and tartrate-resistant acid phosphatase is not confined to osteoclasts but is a general feature of multinucleated giant cells: systematic analysis Rheumatology, May 16, 2013 Evidence Based Medicine Review Article Clinical Article

18 Systemic Sclerosis in Canada's North American Native Population: Assessment of Clinical and Serological Manifestations The Journal of Rheumatology, May 16, 2013 Clinical Article

19 Cholesteryl Ester Transfer Protein in Patients with Rheumatoid Arthritis The Journal of Rheumatology, May 16, 2013 Clinical Article

20 Serum Urate and Incidence of Kidney Disease Among Veterans with Gout The Journal of Rheumatology, May 16, 2013 Clinical Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 How important is vitamin D in preventing infections Osteoporosis International, April 17, 2013 Review Article

2 Association between high sensitivity C-reactive protein, heart rate variability and corrected QT interval in patients with chronic inflammatory arthritis European Journal of Internal Medicine , March 27, 2013

3 Behcets Syndrome Rheumatic Disease Clinics of North America, April 19, 2013 Review Article

4 New treatments for osteoarthritis Current Opinion in Rheumatology, March 29, 2013

5 Update on polymyalgia rheumatica European Journal of Internal Medicine , April 12, 2013

6 Anti-ribosomal P protein IgG autoantibodies in patients with systemic lupus erythematosus: diagnostic performance and clinical profile BMC Medicine, April 9, 2013 Free full text

7 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013

8 Cervical spine manifestations in patients with inflammatory arthritides Nature Reviews Rheumatology , March 27, 2013

9 Treatment strategies for early rheumatoid arthritis Current Opinion in Rheumatology, April 1, 2013

10 Relationship between postmenopausal osteoporosis and the components of clinical sarcopenia Maturitas, April 15, 2013

11 Efficacy and safety of recombinant C1 inhibitor for the treatment of hereditary angioedema attacks: a North American open-label study Annals of Allergy, Asthma, and Immunology, March 29, 2013

12 Rheumatoid arthritis severity: its underlying prognostic factors and how they can be combined to inform treatment decisions International Journal of Clinical Rheumatology, April 12, 2013 Review Article

13 Accuracy of Canadian health administrative databases in identifying patients with rheumatoid arthritis: A validation study using the medical records of rheumatologists Arthritis Care & Research , April 18, 2013

14 Is low-level laser therapy in relieving neck pain effective? Systematic review and meta-analysis Rheumatology International, April 15, 2013 Evidence Based Medicine Review Article

15 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013

16 Association between testosterone levels and risk of future rheumatoid arthritis in men: a population-based case-control study Annals of Rheumatic Diseases, April 9, 2013

17 Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort Annals of Rheumatic Diseases, April 10, 2013

18 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, April 11, 2013

19 Statin Use in Giant Cell Arteritis: A Retrospective Study The Journal of Rheumatology, April 3, 2013

20 Rheumatoid arthritis in the elderly and its relationship with periodontitis: A review Geriatrics and Gerontology International, March 28, 2013 Review Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Rheumatology News & Articles

Articles

Prior Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine