Internal Medicine - Rheumatology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (15) Full Text Articles (143) Focus on Anxiety Disorders

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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141 Successful treatment with tocilizumab in a case of Cogans syndrome complicated with aortitis Modern Rheumatology, May 14, 2013 Clinical Article

142 Spontaneous tendon rupture of the extensor digitrum communis in systemic lupus erythematosus Modern Rheumatology, May 14, 2013

143 Mortality factors in idiopathic inflammatory myopathy: focusing on malignancy and interstitial lung disease Modern Rheumatology, May 14, 2013 Review Article Clinical Article

144 Serum level of APRIL/BLyS in Behcets disease patients: clinical significance in uveitis and disease activity Modern Rheumatology, May 14, 2013 Clinical Article

145 Synovial cyst of the hip in a patient with rheumatoid arthritis Modern Rheumatology, May 14, 2013

146 Differences in clinical manifestations, treatment, and concordance rates with two major sets of criteria for Behcets syndrome for patients in the US and Japan: data from a large, three-center cohort study Modern Rheumatology, May 14, 2013 Clinical Article

147 Layilin, a talin-binding hyaluronan receptor, is expressed in human articular chondrocytes and synoviocytes and is down-regulated by interleukin-1β Modern Rheumatology, May 14, 2013 Review Article

148 A case of Epstein-Barr virus-related lymphadenopathy mimicking the clinical features of IgG4-related disease Modern Rheumatology, May 14, 2013

149 A case of ANCA-associated vasculitis with glomerular eosinophilic infiltration: a possible pathogenic implication Modern Rheumatology, May 14, 2013

150 Four cases of MPO-ANCA-positive vasculitis with otitis media, and review of the literature Modern Rheumatology, May 14, 2013 Review Article

151 JAK inhibitor tofacitinib for treating rheumatoid arthritis: from basic to clinical Modern Rheumatology, May 14, 2013 Clinical Article
Exclusive Author Commentary

152 Takayasu arteritis developing during treatment of ulcerative colitis with infliximab Modern Rheumatology, May 14, 2013 Clinical Article

153 Manipulative Therapy (Feldenkrais, Massage, Chiropractic Manipulation) for Neck Pain Current Rheumatology Reports, May 14, 2013 Clinical Article

154 Update on Oxalate Crystal Disease Current Rheumatology Reports, May 14, 2013 Clinical Article

155 Interleukin-7 and its receptor: The axis of evil to target in Sjogrens syndrome Arthritis & Rheumatism, May 14, 2013 Review Article

156 Enrichment of vitamin D response elements in RA-associated loci supports a role for vitamin D in the pathogenesis of RA Genes and Immunity, May 13, 2013 Clinical Article

157 New biologic therapy for systemic lupus erythematosus Current Opinion in Pharmacology , May 13, 2013 Clinical Article

158 Sphingosine-1-phosphate counteracts interleukin-1β in human chondrocytes Arthritis & Rheumatism, May 13, 2013 Review Article

159 Osteoprotegerin causes apoptosis of endothelial progenitor cells by induction of oxidative stress Arthritis & Rheumatism, May 13, 2013 Review Article

160 Lysophosphatidic acid receptor LPA1 is essential for development of arthritis Arthritis & Rheumatism, May 13, 2013 Clinical Article

50 available pages First Previous 8 9 10 11 12 13 14 15 16 17 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 How important is vitamin D in preventing infections Osteoporosis International, April 17, 2013 Review Article

2 Association between high sensitivity C-reactive protein, heart rate variability and corrected QT interval in patients with chronic inflammatory arthritis European Journal of Internal Medicine , March 27, 2013

3 Behcets Syndrome Rheumatic Disease Clinics of North America, April 19, 2013 Review Article

4 New treatments for osteoarthritis Current Opinion in Rheumatology, March 29, 2013

5 Update on polymyalgia rheumatica European Journal of Internal Medicine , April 12, 2013

6 Anti-ribosomal P protein IgG autoantibodies in patients with systemic lupus erythematosus: diagnostic performance and clinical profile BMC Medicine, April 9, 2013 Free full text

7 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013

8 Cervical spine manifestations in patients with inflammatory arthritides Nature Reviews Rheumatology , March 27, 2013

9 Treatment strategies for early rheumatoid arthritis Current Opinion in Rheumatology, April 1, 2013

10 Relationship between postmenopausal osteoporosis and the components of clinical sarcopenia Maturitas, April 15, 2013

11 Efficacy and safety of recombinant C1 inhibitor for the treatment of hereditary angioedema attacks: a North American open-label study Annals of Allergy, Asthma, and Immunology, March 29, 2013

12 Rheumatoid arthritis severity: its underlying prognostic factors and how they can be combined to inform treatment decisions International Journal of Clinical Rheumatology, April 12, 2013 Review Article

13 Accuracy of Canadian health administrative databases in identifying patients with rheumatoid arthritis: A validation study using the medical records of rheumatologists Arthritis Care & Research , April 18, 2013

14 Is low-level laser therapy in relieving neck pain effective? Systematic review and meta-analysis Rheumatology International, April 15, 2013 Evidence Based Medicine Review Article

15 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013

16 Association between testosterone levels and risk of future rheumatoid arthritis in men: a population-based case-control study Annals of Rheumatic Diseases, April 9, 2013

17 Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort Annals of Rheumatic Diseases, April 10, 2013

18 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, April 11, 2013

19 Statin Use in Giant Cell Arteritis: A Retrospective Study The Journal of Rheumatology, April 3, 2013

20 Rheumatoid arthritis in the elderly and its relationship with periodontitis: A review Geriatrics and Gerontology International, March 28, 2013 Review Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Rheumatology News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine