Internal Medicine - Rheumatology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (18) Full Text Articles (143) Focus on HIV

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

41 Reduction of plasma IL-6 but not TNF-α by methotrexate in patients with early rheumatoid arthritis: a potential biomarker for radiographic progression Clinical Rheumatology, June 14, 2013 Clinical Article

42 Should Pneumocystis jiroveci prophylaxis be recommended with Rituximab treatment in ANCA-associated vasculitis Clinical Rheumatology, June 14, 2013 Clinical Article
Exclusive Author Commentary

43 Baseline sacroiliac joint magnetic resonance imaging abnormalities and male sex predict the development of radiographic sacroiliitis Clinical Rheumatology, June 14, 2013 Review Article

44 Effect of exercise on the plasma BDNF levels in elderly women with knee osteoarthritis Rheumatology International, June 14, 2013 Clinical Article

45 No evidence of association between CTLA-4 polymorphisms and systemic lupus erythematosus in Iranian patients International Journal of Rheumatic Diseases, June 14, 2013 Review Article

46 Manual therapy and therapeutic exercise in the treatment of osteoarthritis of the hip: a systematic review Full Text Rheumatismo, June 14, 2013 Evidence Based Medicine Review Article Clinical Article

47 Bosentan and sildenafil: successful treatment in a sclerodermic patient with refractory ulcers Full Text Rheumatismo, June 14, 2013 Clinical Article

48 Granulomatosis polyangiitis associated with meningeal involvement: response to rituximab therapy after failure of cyclophosphamide Full Text Rheumatismo, June 14, 2013 Clinical Article

49 Achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritis Full Text Rheumatismo, June 14, 2013 Clinical Article

50 Unilateral RS3PE syndrome Full Text Turkish Journal of Rheumatology, June 14, 2013

51 Relationship between the functional exon 3 deleted growth hormone receptor polymorphism and symptomatic osteoarthritis in women Annals of Rheumatic Diseases, June 14, 2013 Clinical Article

52 EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis Annals of Rheumatic Diseases, June 14, 2013 Evidence Based Medicine Clinical Article

53 Relatives without rheumatoid arthritis show reactivity to anti-citrullinated protein/peptide antibodies which are associated with arthritis-related traits: Studies of the etiology of rheumatoid arthritis Arthritis & Rheumatism, June 14, 2013 Clinical Article

54 Outcome of pregnancy in Italian patients with primary sjogren syndrome The Journal of Rheumatology, June 14, 2013 Review Article

55 Castlemans disease combined with the development of systemic lupus erythematosus Full Text Turkish Journal of Rheumatology, June 14, 2013

56 The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis Annals of Rheumatic Diseases, June 14, 2013 Clinical Article

57 Identification of the NF-kB activating protein-like locus as a risk locus for rheumatoid arthritis Annals of Rheumatic Diseases, June 14, 2013 Clinical Article

58 Myopericarditis, as the first sign of rheumatoid arthritis relapse, evaluated by cardiac magnetic resonance Inflammation & Allergy - Drug Targets, June 14, 2013 Clinical Article

59 Therapies for active rheumatoid arthritis after methotrexate failure New England Journal of Medicine, June 13, 2013 Evidence Based Medicine Clinical Article

60 The circadian clock in chondrocytes regulates genes controlling key aspects of cartilage homeostasis Arthritis & Rheumatism, June 13, 2013 Review Article

50 available pages First Previous 3 4 5 6 7 8 9 10 11 12 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

Read the article summary

CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Med Articles

Last month's top read Top Articles of 2012

1 Use of New Oral Anticoagulants in Antiphospholipid Syndrome Current Rheumatology Reports, May 7, 2013

2 Intra-articular glucocorticoids for acute gout Cochrane Reviews, May 3, 2013

3 The role of vitamin D supplementation in patients with rheumatic diseases Nature Reviews Rheumatology , May 15, 2013 Clinical Guideline

4 Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial The Lancet, May 16, 2013

5 Antineutrophil cytoplasmic antibody-associated vasculitides: is it time to split up the group Annals of Rheumatic Diseases, May 8, 2013 Review Article

6 The risk of gastrointestinal perforations in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the BSRBR-RA Annals of Rheumatic Diseases, May 8, 2013

7 Changes in biomarkers after therapeutic intervention in temporal arteries cultured in Matrigel: a new model for preclinical studies in giant-cell arteritis Annals of Rheumatic Diseases, May 7, 2013

8 Whipples disease Annals of Rheumatic Diseases, May 24, 2013 Review Article

9 Osteoporosis treatment European Journal of Internal Medicine , April 24, 2013

10 Comparison of Intra-Articular Hyaluronic Acid Injections with Transcutaneous Electric Nerve Stimulation for the Management of Knee Osteoarthritis: A Randomized Controlled Trial Archives of Physical Medicine and Rehabilitation, April 30, 2013

11 Vitamin D and systemic lupus erythematosus: an update Expert Review of Clinical Immunology, May 9, 2013 Review Article

12 Calcium and Vitamin D intake and mortality: results from the canadian multicentre osteoporosis study (camos) Journal of Clinical Endocrinology and Metabolism, May 24, 2013

13 Not all joint pain is arthritis Cleveland Clinic Journal of Medicine, May 8, 2013 Free full text

14 New classification criteria for gout: a framework for progress Rheumatology, April 24, 2013

15 Anti-cyclic citrullinated peptide assays differ in subjects at elevated risk for rheumatoid arthritis and subjects with established disease Arthritis & Rheumatism, May 20, 2013

16 MRI-based three-dimensional bone shape of the knee predicts onset of knee osteoarthritis: Data from the Osteoarthritis Initiative Arthritis & Rheumatism, May 6, 2013

17 Rheumatoid arthritis, anti-tumour necrosis factor therapy, and risk of malignant melanoma: nationwide population based prospective cohort study from Sweden British Medical Journal, April 23, 2013

18 Old drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs? BMC Medicine, February 12, 2013 Free full text

19 How many life years are lost in patients with rheumatoid arthritis? Secular cause-specific and all-cause mortality in rheumatoid arthritis, and their predictors in a long-term Australian cohort study Internal Medicine Journal, February 12, 2013

20 Anakinra treatment in patients with refractory inflammatory myopathies and possible predictive response biomarkers: a mechanistic study with 12 months follow-up Annals of Rheumatic Diseases, May 8, 2013

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Rheumatology News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Med Articles

Other Topics in Internal Medicine