Internal Medicine - Rheumatology News & Articles

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Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (9) Full Text Articles (143) Focus on GERD & PUD

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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21 Patients needs and expectations with regard to rheumatology nursing care: results of multicentre focus group interviews Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

22 Induction therapy with adalimumab plus methotrexate for 24 weeks followed by methotrexate monotherapy up to week 48 versus methotrexate therapy alone for DMARD-naive patients with early rheumatoid arthritis: HIT HARD, an investigator-initiated study Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

23 Co-localisation of non-cartilaginous articular pathology increases risk of cartilage loss in the tibiofemoral joint--the MOST study Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

24 Microarray-based gene expression profiling in patients with cryopyrin-associated periodic syndromes defines a disease-related signature and IL-1-responsive transcripts Annals of Rheumatic Diseases, May 21, 2013 Review Article

25 A randomised, double-blind, parallel-group study to demonstrate equivalence in efficacy and safety of CT-P13 compared with innovator infliximab when coadministered with methotrexate in patients with active rheumatoid arthritis: the PLANETRA study Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

26 Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data Annals of Rheumatic Diseases, May 21, 2013 Review Article

27 A preliminary algorithm introducing immunogenicity assessment in the management of patients with RA receiving tumour necrosis factor inhibitor therapies Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

28 Patient satisfaction with nursing consultations in a rheumatology outpatient clinic: a 21-month randomised controlled trial in patients with inflammatory arthritides Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

29 Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment Annals of Rheumatic Diseases, May 21, 2013 Review Article

30 Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis Annals of Rheumatic Diseases, May 21, 2013 Review Article

31 In erosive hand osteoarthritis more inflammatory signs on ultrasound are found than in the rest of hand osteoarthritis Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

32 Anti-TNF treatment blocks the induction of T cell-dependent humoral responses Annals of Rheumatic Diseases, May 21, 2013 Review Article

33 Granulocyte colony stimulating factor exacerbates antineutrophil cytoplasmic antibody vasculitis Annals of Rheumatic Diseases, May 21, 2013 Review Article

34 MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes Annals of Rheumatic Diseases, May 21, 2013 Review Article

35 Primary Sjogrens syndrome and malignancy risk: a systematic review and meta-analysis Annals of Rheumatic Diseases, May 21, 2013 Evidence Based Medicine Review Article Clinical Article

36 The cellular composition of lymph nodes in the earliest phase of inflammatory arthritis Annals of Rheumatic Diseases, May 21, 2013 Review Article

37 Progression of osteoarthritis as a state of inertia Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

38 Cam impingement causes osteoarthritis of the hip: a nationwide prospective cohort study (CHECK) Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

39 Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

40 Methotrexate polyglutamation in relation to infliximab pharmacokinetics in rheumatoid arthritis Annals of Rheumatic Diseases, May 21, 2013 Clinical Article

50 available pages First Previous 2 3 4 5 6 7 8 9 10 11 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 How important is vitamin D in preventing infections Osteoporosis International, April 17, 2013 Review Article

2 Association between high sensitivity C-reactive protein, heart rate variability and corrected QT interval in patients with chronic inflammatory arthritis European Journal of Internal Medicine , March 27, 2013

3 Behcets Syndrome Rheumatic Disease Clinics of North America, April 19, 2013 Review Article

4 New treatments for osteoarthritis Current Opinion in Rheumatology, March 29, 2013

5 Update on polymyalgia rheumatica European Journal of Internal Medicine , April 12, 2013

6 Anti-ribosomal P protein IgG autoantibodies in patients with systemic lupus erythematosus: diagnostic performance and clinical profile BMC Medicine, April 9, 2013 Free full text

7 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013

8 Cervical spine manifestations in patients with inflammatory arthritides Nature Reviews Rheumatology , March 27, 2013

9 Treatment strategies for early rheumatoid arthritis Current Opinion in Rheumatology, April 1, 2013

10 Relationship between postmenopausal osteoporosis and the components of clinical sarcopenia Maturitas, April 15, 2013

11 Efficacy and safety of recombinant C1 inhibitor for the treatment of hereditary angioedema attacks: a North American open-label study Annals of Allergy, Asthma, and Immunology, March 29, 2013

12 Rheumatoid arthritis severity: its underlying prognostic factors and how they can be combined to inform treatment decisions International Journal of Clinical Rheumatology, April 12, 2013 Review Article

13 Accuracy of Canadian health administrative databases in identifying patients with rheumatoid arthritis: A validation study using the medical records of rheumatologists Arthritis Care & Research , April 18, 2013

14 Is low-level laser therapy in relieving neck pain effective? Systematic review and meta-analysis Rheumatology International, April 15, 2013 Evidence Based Medicine Review Article

15 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013

16 Association between testosterone levels and risk of future rheumatoid arthritis in men: a population-based case-control study Annals of Rheumatic Diseases, April 9, 2013

17 Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort Annals of Rheumatic Diseases, April 10, 2013

18 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, April 11, 2013

19 Statin Use in Giant Cell Arteritis: A Retrospective Study The Journal of Rheumatology, April 3, 2013

20 Rheumatoid arthritis in the elderly and its relationship with periodontitis: A review Geriatrics and Gerontology International, March 28, 2013 Review Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Rheumatology News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine