Internal Medicine - Pulmonology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (11) Full Text Articles (830) Focus on HIV

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

181 Cystic Fibrosis Pulmonary Guidelines American Journal of Respiratory and Critical Care Medicine, May 2, 2013 Clinical Guideline

182 Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK British Journal of Cancer, May 2, 2013 Clinical Article

183 Impact of positive chest X-ray findings and blood cultures on adverse outcomes following hospitalized pneumococcal lower respiratory tract infection: a population-based cohort study Full Text BMC Infectious Diseases, May 2, 2013 Clinical Article

184 Replication Study in Chinese Population and Meta-Analysis Supports Association of the 5p15.33 Locus with Lung Cancer PLOS ONE, May 2, 2013 Evidence Based Medicine

185 Periodontitis and systemic diseases: a record of discussions of working group 4 of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases Journal of Clinical Periodontology, May 2, 2013 Review Article

186 Periodontal systemic associations: review of the evidence Journal of Clinical Periodontology, May 2, 2013 Review Article Clinical Article

187 Adhesion molecules in subjects with COPD and healthy non-smokers: a cross sectional parallel group study Full Text Respiratory Research, May 2, 2013 Clinical Article

188 Central sleep apnea and complex sleep apnea in patients with epilepsy Sleep and Breathing, May 2, 2013 Clinical Article

189 An update on molecularly targeted therapies in second- and third-line treatment in non-small cell lung cancer: focus on EGFR inhibitors and anti-angiogenic agents Clinical and Translational Oncology, May 2, 2013 Review Article Clinical Article

190 The CURB-65 scoring system in severity assessment of Eastern Nigerian patients with community-acquired pneumonia: a prospective observational study Full Text Primary Care Respiratory Journal, May 2, 2013 Clinical Article

191 Effects of age on H1N1-specific serum IgG1 and IgG3 levels evaluated during the 2011-2012 influenza vaccine season Full Text Immunity & Ageing, May 2, 2013 Clinical Article

192 Pooled Analysis of the Prognostic and Predictive Effects of KRAS Mutation Status and KRAS Mutation Subtype in Early-Stage Resected Non-Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy Journal of Clinical Oncology, May 2, 2013 Clinical Article

193 Obesity in Asthma: Approaches to Treatment Current Allergy and Asthma Reports, May 1, 2013 Review Article

194 Next-Generation Sequencing Reveals High Concordance of Recurrent Somatic Alterations Between Primary Tumor and Metastases From Patients With Non-Small-Cell Lung Cancer Journal of Clinical Oncology, May 1, 2013 Clinical Article

195 Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells International Journal of Cancer, May 1, 2013 Clinical Article

196 Risk factors for pulmonary tuberculosis in patients with chronic obstructive airway disease in Taiwan: a nationwide cohort study Full Text BMC Infectious Diseases, May 1, 2013 Clinical Article
Exclusive Author Commentary

197 Improvement in process of care and outcome in patients requiring intensive care unit admission for community acquired pneumonia Full Text BMC Infectious Diseases, May 1, 2013 Clinical Article

198 Vascular responsiveness in patients with chronic obstructive pulmonary disease (COPD) European Journal of Internal Medicine , May 1, 2013 Clinical Article

199 TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells Cancer Letters, May 1, 2013 Clinical Article

200 Differential Effects on Lung Cancer Cell Proliferation by Agonists of Glucocorticoid and PPAR Receptors Molecular Carcinogenesis, May 1, 2013 Clinical Article

50 available pages First Previous 10 11 12 13 14 15 16 17 18 19 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events Cochrane Reviews, April 2, 2013 Review Article

2 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article

3 Three phenotypes of adult-onset asthma Allergy, April 19, 2013 Review Article

4 Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies British Medical Journal, April 10, 2013 Free full text

5 Does aspirin use prevent acute coronary syndrome in patients with pneumonia: multicenter prospective randomized trial Coronary Artery Disease, April 12, 2013

6 Effect of Azithromycin Maintenance Treatment on Infectious Exacerbations Among Patients With Non–Cystic Fibrosis Bronchiectasis: The BAT Randomized Controlled Trial JAMA, March 27, 2013 Evidence Based Medicine

7 Peripheral lung function in patients with stable and unstable asthma The Journal of Allergy and Clinical Immunology, April 8, 2013

8 Invasive mechanical ventilation in acute coronary syndromes in the era of percutaneous coronary intervention European Heart Journal: Acute Cardiovascular Care, April 16, 2013

9 Inhaled corticosteroids for subacute and chronic cough in adults Cochrane Reviews, April 11, 2013

10 Lack of a relation between serum 25(OH)D concentrations and asthma in adolescents American Journal of Clinical Nutrition, April 18, 2013

11 Asthma outcomes and costs of therapy with extrafine beclomethasone and fluticasone The Journal of Allergy and Clinical Immunology, April 16, 2013

12 Predictors of early dyspnoea relief in acute heart failure and the association with 30-day outcomes: findings from ASCEND-HF European Journal of Heart Failure, March 27, 2013

13 Sublingual Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and Asthma: A Systematic Review JAMA, March 27, 2013 Evidence Based Medicine

14 Application of appropriateness criteria for hospitalization in COPD exacerbation Internal and Emergency Medicine, April 5, 2013

15 Ciclesonide versus other inhaled corticosteroids for chronic asthma in children Cochrane Reviews, March 7, 2013 Review Article

16 Effect of Long-term, Low-Dose Erythromycin on Pulmonary Exacerbations Among Patients With Non–Cystic Fibrosis Bronchiectasis: The BLESS Randomized Controlled Trial JAMA, March 27, 2013 Evidence Based Medicine

17 Identification of patients with low-risk pulmonary embolism suitable for outpatient treatment using the pulmonary embolism severity index (PESI) Irish Journal of Medical Science, March 26, 2013

18 Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: meta-analysis of randomised controlled trials European Journal of Clinical Microbiology & Infectious Diseases, April 10, 2013 Evidence Based Medicine

19 Characteristics of Lung Cancers Detected by Computer Tomography Screening in the Randomized NELSON Trial American Journal of Respiratory and Critical Care Medicine, April 18, 2013

20 Combination therapy in the management of pulmonary arterial hypertension International Journal of Clinical Practice, April 15, 2013 Review Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Pulmonology News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine