Internal Medicine - Nephrology/Urology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (15) Full Text Articles (441) Focus on HIV

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 Kidney stones: A fetal origins hypothesis Journal of Bone and Mineral Research, May 24, 2013 Review Article

2 Quantitative analysis of multiparametric prostate mr images: differentiation between prostate cancer and normal tissue and correlation with gleason score—a computer-aided diagnosis development study Radiology, May 24, 2013 Clinical Article

3 Prognostic interest in discriminating muscularis mucosa invasion (t1a vs t1b) in nonmuscle invasive bladder carcinoma: french national multicenter study with central pathology review The Journal of Urology, May 24, 2013 Clinical Article

4 Pseudocarcinomatous urothelial hyperplasia of the bladder: clinical findings and followup of 70 patients The Journal of Urology, May 24, 2013 Review Article

5 Diagnosis and treatment of erectile dysfunction for reduction of cardiovascular risk The Journal of Urology, May 24, 2013 Clinical Article

6 Recent advances in the treatment of metastatic renal cell carcinoma International Journal of Urology, May 24, 2013 Clinical Article

7 Differences in prostate cancer detection rates according to the level of glomerular filtration rate in patients with prostate specific antigen levels of 4.0-10.0 ng/ml International Journal of Clinical Practice, May 24, 2013 Clinical Article

8 Patient demographics, quality of life, and disease features of men with newly diagnosed prostate cancer: trends in the PSA era Urology, May 24, 2013 Clinical Article

9 A phase II trial of neoadjuvant nab-paclitaxel, carboplatin, and gemcitabine (ACAG) in patients with locally advanced carcinoma of the bladder Urology, May 24, 2013 Clinical Article

10 Peritoneal dialysis in patients with refractory congestive heart failure: potential prognostic factors Blood Purification, May 24, 2013 Clinical Article

11 Sexual dysfunction predicts depression among women on hemodialysis International Urology and Nephrology, May 24, 2013 Clinical Article

12 Development and validation of the Chinese Overactive Bladder Symptom Score for assessing overactive bladder syndrome in a RESORT study Journal of the Formosan Medical Association, May 24, 2013 Clinical Article

13 The evaluation of CT urography in the haematuria clinic Journal of Clinical Urology, May 24, 2013 Clinical Article

14 Importance of local data on occurrence and outcomes of renal cell cancer Journal of Clinical Urology, May 24, 2013 Clinical Article

15 Tumour multiplicity as a risk factor for the development of bladder tumours after primary upper urinary tract cancer Journal of Clinical Urology, May 24, 2013

Prior Articles

16 Nanoparticle albumin-bound paclitaxel for second-line treatment of metastatic urothelial carcinoma: a single group, multicentre, phase 2 study The Lancet Oncology, May 23, 2013 Clinical Article

17 Urinary flavonoid excretion and risk of acute coronary syndrome in a nested case-control study American Journal of Clinical Nutrition, May 23, 2013 Clinical Article

18 Adherence to antihypertensive agents improves risk reduction of end-stage renal disease Kidney International, May 23, 2013 Clinical Article

19 LDL cholesterol in CKD-to treat or not to treat? Kidney International, May 23, 2013 Clinical Article

20 Update on cystatin C: Incorporation into clinical practice American Journal of Kidney Diseases, May 23, 2013 Review Article Clinical Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Internal Medicine - Nephrology/Urology News & Articles

Articles

Prior Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine