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Internal Medicine - Nephrology/Urology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (15) Full Text Articles (441) Focus on Thyroid Disease
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

921 Safety and efficacy of everolimus in Chinese patients with metastatic renal cell carcinoma resistant to vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy: an open-label phase 1b study Full Text BMC Cancer, March 22, 2013    Review Article

922 Active surveillance for low-risk bladder cancer Urologic Oncology: Seminars and Original Investigations, March 22, 2013    Clinical Article

923 Comparison of absolute serum creatinine changes versus Kidney Disease: Improving Global Outcomes consensus definitions for characterizing stages of acute kidney injury Nephrology Dialysis Transplantation, March 22, 2013    Clinical Article

924 A review of tasquinimod in the treatment of advanced prostate cancer Full Text Drug Design, Development and Therapy, March 22, 2013    Review Article    Clinical Article

925 Proximal bulbar periurethral abscess Full Text International Braz J Urol, March 22, 2013

926 Differencial proteome of clear-cell renal cell carcinoma (ccRCC) tissues Full Text International Braz J Urol, March 22, 2013    Clinical Article

927 2D map of proteins from human renal stone matrix and evaluation of their effect on oxalate induced renal tubular epithelial cell injury Full Text International Braz J Urol, March 22, 2013    Clinical Article

928 Prevalence and risk factors for penile lesions/anomalies in a cohort of Brazilian men = 40 years of age Full Text International Braz J Urol, March 22, 2013    Clinical Article

929 Ultrasonography-guided PNL in comparison with laparoscopic ureterolithotomy in the management of large proximal ureteral stone Full Text International Braz J Urol, March 22, 2013    Clinical Article

930 Results of urinary dissolution therapy for radiolucent calculi Full Text International Braz J Urol, March 22, 2013

931 Evaluation of acute toxicity and symptoms palliation in a hypofractionated weekly schedule of external radiotherapy for elderly patients with muscular invasive bladder cancer Full Text International Braz J Urol, March 22, 2013

932 Complications and quality of life after template-assisted transperineal prostate biopsy in patients eligible for focal therapy Urology, March 22, 2013    Clinical Article

933 Clinical judgment versus biomarker prostate cancer gene 3: which is best when determining the need for repeat prostate biopsy? Urology, March 22, 2013    Clinical Article

934 Relationship between T2 relaxation and apparent diffusion coefficient in malignant and non-malignant prostate regions and the effect of peripheral zone fractional volume British Journal of Radiology, March 22, 2013    Clinical Article

935 Solifenacin improves double-J stent-related symptoms in both genders following uncomplicated ureteroscopic lithotripsy Urological Research - Urolithiasis, March 22, 2013    Clinical Article

936 Nationwide survey on current treatments for IgA nephropathy in Japan Clinical and Experimental Nephrology, March 22, 2013    Clinical Article

937 Clinical audit improves hypertension control in hemodialysis patients The International Journal of Artificial Organs, March 22, 2013    Clinical Article

938 Electrocardiographic P-wave characteristics in patients with end-stage renal disease: P-index and interatrial block International Urology and Nephrology, March 22, 2013    Clinical Article

939 Low serum pancreatic enzyme levels predict mortality and are associated with malnutrition-inflammation-atherosclerosis syndrome in patients with chronic kidney disease International Urology and Nephrology, March 22, 2013    Clinical Article

940 HLA DRB1 Alleles and Hepatitis C Virus Infection in Chronic Kidney Disease Patients Renal Failure, March 22, 2013    Clinical Article

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Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Statin use and risk of prostate cancer and high-grade prostate cancer: results from the REDUCE study Prostate Cancer & Prostatic Diseases, April 11, 2013

2 Antihypertensive Efficacy of Olmesartan Medoxomil and Ramipril in Elderly Patients with Mild to Moderate Hypertension Grouped According to Renal Function Status High Blood Pressure & Cardiovascular Prevention, April 16, 2013

3 Lifetime Incidence of CKD Stages 3-5 in the United States American Journal of Kidney Diseases, April 9, 2013

4 Detecting and controlling diabetic nephropathy: What do we know? Cleveland Clinic Journal of Medicine, April 3, 2013    Free full text

5 Strategy for detection of prostate cancer based on relation between prostate specific antigen at age 40-55 and long term risk of metastasis: case-control study British Medical Journal, April 23, 2013

6 Effective elimination of dabigatran by haemodialysis Thrombosis and Haemostasis, April 12, 2013

7 Chlorthalidone Versus Hydrochlorothiazide for the Treatment of Hypertension in Older Adults A Population-Based Cohort Study Annals of Internal Medicine, March 19, 2013

8 Kidney Cancer and Diabetes Mellitus: A Population-Based Case-Control Study in Taiwan Annals, Academy of Medicine, Singapore, April 4, 2013    Free full text

9 Outcomes Associated With Microalbuminuria Effect Modification by Chronic Kidney Disease JACC - Journal of the American College of Cardiology, April 12, 2013    Free full text

10 Managing the difficult penile prosthesis patient The Journal of Sexual Medicine, April 8, 2013

11 Blood Urea Nitrogen/Creatinine Ratio Identifies a High-Risk but Potentially Reversible Form of Renal Dysfunction in Patients With Decompensated Heart Failure Circulation: Heart Failure, March 26, 2013    Review Article

12 Mortality Predictability of Body Size and Muscle Mass Surrogates in Asian vs White and African American Hemodialysis Patients Mayo Clinic Proceedings, April 9, 2013    Evidence Based Medicine

13 An open-label, long-term evaluation of the safety, efficacy and tolerability of avanafil in male patients with mild to severe erectile dysfunction International Journal of Clinical Practice, April 9, 2013

14 Current State of Endovascular Treatment for Vasculogenic Erectile Dysfunction Current Cardiology Reports, April 8, 2013

15 Type 2 Translational Research for CKD Clinical Journal of the American Society of Nephrology, April 29, 2013

16 Frequency of Acute Kidney Injury Following Intravenous Contrast Medium Administration: A Systematic Review and Meta-Analysis Radiology, March 29, 2013    Evidence Based Medicine    Review Article

17 Canadian Society of Nephrology Guidelines for the Management of Patients With ESRD Treated With Intensive Hemodialysis American Journal of Kidney Diseases, April 9, 2013

18 Predictors of diabetic nephropathy Central European Journal of Medicine, April 23, 2013

19 Renin-Angiotensin System Blockers May Create More Risk Than Reward for Sodium-Depleted Cardiovascular Patients With High Plasma Renin Levels American Journal of Hypertension, April 8, 2013    Free full text

20 Non-steroidal anti-inflammatory drugs and chronic kidney disease progression: a systematic review Family Practice, January 10, 2013    Evidence Based Medicine
Exclusive Author Commentary

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicinemore

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