Internal Medicine - Nephrology/Urology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Latest (19) Full Text Articles (441) Focus on Angina

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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801 Treatment patterns, risk factor control and functional capacity in patients with cardiovascular and chronic kidney disease in the cardiac rehabilitation setting European Journal of Preventive Cardiology, March 26, 2013 Clinical Article

802 Sargramostim (GM-CSF) and lenalidomide in castration-resistant prostate cancer (CRPC): Results from a phase I-II clinical trial Urologic Oncology: Seminars and Original Investigations, March 26, 2013 Clinical Article

803 Down-Expression of LRP1B Promotes Cell Migration via RhoA/Cdc42 pathway and actin cytoskeleton remodeling in RCC Cancer Science, March 26, 2013 Clinical Article

804 Androgens regulate TRAIL-induced cell death in prostate cancer cells via multiple mechanisms Cancer Letters, March 26, 2013 Clinical Article

805 Management of Gouty Arthritis in Patients With Chronic Kidney Disease American Journal of Therapeutics, March 26, 2013 Clinical Article

806 Optimal number of biopsies and impact of testicular histology on the outcome of testicular sperm extraction Full Text Urology Journal, March 26, 2013 Clinical Article

807 Contribution of Glomerular Filtration Rate to 10-Year Cardiovascular and Mortality Risk Among Hypertensive Adults: Tehran Lipid and Glucose Study The Journal of Clinical Hypertension, March 26, 2013 Clinical Article

808 Quality-of-Care Indicators Among Remote-Dwelling Hemodialysis Patients: A Cohort Study American Journal of Kidney Diseases, March 26, 2013 Clinical Article

809 Comparison of alternative primary outcome measures for use in a lupus nephritis trial Arthritis & Rheumatism, March 26, 2013 Clinical Article

810 Effect of CD40 and sCD40L on Renal Function and Survival in Patients With Renal Artery Stenosis Hypertension, March 26, 2013 Review Article

811 Plasma carotenoid- and retinol-weighted gene scores and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium Cancer Epidemiology, Biomarkers & Prevention, March 26, 2013 Clinical Article

812 Progression of chronic kidney disease in a multi-ethnic community cohort of patients with diabetes mellitus Diabetic Medicine, March 25, 2013 Clinical Article

813 Intake of fiber and fiber-rich plant foods is associated with a lower risk of renal cell carcinoma in a large US cohort American Journal of Clinical Nutrition, March 25, 2013 Clinical Article

814 Impact of lower urinary tract symptoms on prostate cancer risk among Japanese men with prostate-specific antigen <10 ng/mL and non-suspicious digital rectal examination International Journal of Urology, March 25, 2013 Clinical Article

815 Active surveillance of very-low-risk prostate cancer in the setting of active treatment of benign prostatic hyperplasia with 5α-reductase inhibitors Urology, March 25, 2013 Clinical Article

816 Predictors of successful first-line antimuscarinic monotherapy in men with enlarged prostate and predominant storage symptoms Urology, March 25, 2013 Clinical Article

817 Antibiotic treatment of urinary tract infection by community pharmacists: a cross-sectional study British Journal of General Practice, March 25, 2013 Clinical Article

818 Clinical features of kidney cancer in primary care: a case-control study using primary care records British Journal of General Practice, March 25, 2013 Clinical Article

819 Adherence to a Healthy Lifestyle and All-Cause Mortality in CKD Clinical Journal of the American Society of Nephrology, March 25, 2013 Clinical Guideline Clinical Article

820 The prostate cancer blocking potential of the histone deacetylase inhibitor LBH589 is not enhanced by the multi receptor tyrosine kinase inhibitor TKI258 Investigational New Drugs, March 25, 2013 Clinical Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Internal Medicine - Nephrology/Urology News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine