Internal Medicine - Infectious Disease News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (51) Full Text Articles (1098) Focus on Diabetes Mellitus

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

121 Atmospheric moisture variability and transmission of hemorrhagic fever with renal syndrome in Changsha City, mainland China, 1991-2010 Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

122 Host resistance, population structure and the long-term persistence of bubonic plague: contributions of a modelling approach in the malagasy focus Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

123 Cell patterns emerge from coupled chemical and physical fields with cell proliferation dynamics: The arabidopsis thaliana root as a study system Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

124 Human La protein interaction with GCAC near the initiator AUG enhances hepatitis C virus RNA replication by promoting linkage between 5' and 3' untranslated regions Journal of Virology, June 17, 2013 Review Article

125 Toscana virus NSs protein inhibits the induction of type I interferon by interacting with RIG-I Journal of Virology, June 17, 2013 Review Article

126 HIV-1 envelope glycoprotein trimers display open quaternary conformation when bound to the gp41 membrane-proximal external-region-directed broadly neutralizing antibody Z13e1 Journal of Virology, June 17, 2013 Review Article

127 Structural changes in dengue virus when exposed to a temperature of 37°c Journal of Virology, June 17, 2013 Review Article

128 The lack of maturation of ebola virus-infected dendritic cells results from the cooperative effect of at least two viral domains Journal of Virology, June 17, 2013 Review Article

129 Divergent kinetics of proliferating T cell subsets in simian immunodeficiency virus (SIV) infection: SIV eliminates the “first responder” CD4+ T cells in primary infection Journal of Virology, June 17, 2013 Review Article

130 Suppressed Th17 levels correlate with elevated PIAS3, SHP2, and SOCS3 expression in CD4 T cells during acute simian immunodeficiency virus infection Journal of Virology, June 17, 2013 Review Article

131 Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells Journal of Virology, June 17, 2013 Review Article

132 Novel recombinant hepatitis B virus vectors efficiently deliver protein and RNA encoding genes into primary hepatocytes Journal of Virology, June 17, 2013 Review Article

133 Potential of herpesvirus saimiri-based vectors to reprogram a somatic ewing's sarcoma family tumor cell line Journal of Virology, June 17, 2013 Review Article

134 Inhibition of hepatitis C virus (HCV) replication by specific RNA aptamers against HCV NS5B RNA replicase Journal of Virology, June 17, 2013 Review Article
Exclusive Author Commentary

135 Attenuated and replication-competent vaccinia virus strains M65 and M101 with distinct biology and immunogenicity as potential vaccine candidates against pathogens Journal of Virology, June 17, 2013 Review Article

136 HIV-1 Vpu does not degrade interferon regulatory factor 3 Journal of Virology, June 17, 2013 Review Article

137 Inhibition of the HIV-1 spike by single-PG9/16-antibody binding suggests a coordinated-activation model for its three protomeric units Journal of Virology, June 17, 2013 Review Article

138 Evidence in support of RNA-mediated inhibition of phosphatidylserine-dependent HIV-1 gag membrane binding in cells Journal of Virology, June 17, 2013 Review Article

139 CD27-CD70 costimulation controls T cell immunity during acute and persistent cytomegalovirus infection Journal of Virology, June 17, 2013 Review Article

140 Antiviral activity of trappin-2 and elafin in vitro and in vivo against genital herpes Journal of Virology, June 17, 2013 Review Article

50 available pages First Previous 7 8 9 10 11 12 13 14 15 16 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

Read the article summary

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

Read the article summary

CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Med Articles

Last month's top read Top Articles of 2012

1 Urinary Tract Infections: Current and Emerging Management Strategies Clinical Infectious Diseases, May 6, 2013

2 Infective Endocarditis New England Journal of Medicine, April 24, 2013 Review Article

3 Eyebrow hairs from actinic keratosis patients harbor the highest number of cutaneous human papillomaviruses BMC Infectious Diseases, April 30, 2013 Free full text

4 Tapeworm Infection of the Brain JAMA, May 16, 2013 Evidence Based Medicine Review Article

5 Outcomes After Acute Myocardial Infarction in HIV-Infected Patients Circulation, May 1, 2013

6 Colistin and Rifampicin compared with Colistin alone for the treatment of serious infections due to extensively drug-resistant Acinetobacter baumannii. A multicentre, randomised, clinical trial Clinical Infectious Diseases, May 2, 2013

7 Update on rilpivirine: A new potent non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV replication Annals of Medicine, May 22, 2013 Evidence Based Medicine

8 Delayed antibiotics for respiratory infections Cochrane Reviews, May 13, 2013 Evidence Based Medicine

9 Does empirical Clostridium difficile Infection (CDI) therapy result in false-negative CDI diagnostic test results Clinical Infectious Diseases, May 24, 2013

10 Treatment of delta hepatitis Expert Review of Anti-infective Therapy, May 7, 2013

11 Natural History of Anal vs Oral HPV Infection in HIV-Infected Men and Women The Journal of Infectious Diseases, May 15, 2013

12 Immunogenicity of 2 Doses of HPV Vaccine in Younger Adolescents vs 3 Doses in Young Women A Randomized Clinical Trial Immunogenicity of HPV Vaccine in Girls vs Women JAMA, May 6, 2013 Evidence Based Medicine

13 A Risk for Hepatocellular Carcinoma Persists Long-term After Sustained Virologic Response in Patients With Hepatitis C-Associated Liver Cirrhosis Clinical Infectious Diseases, May 16, 2013

14 Outpatient parenteral antibiotic therapy: Principles and practice European Journal of Internal Medicine , April 25, 2013

15 Interventions to improve antibiotic prescribing practices for hospital inpatients Cochrane Reviews, May 16, 2013 Evidence Based Medicine

16 Understanding the Determinants of Antimicrobial Prescribing Within Hospitals: The Role of Prescribing Etiquette Clinical Infectious Diseases, May 9, 2013

17 Proton Pump Inhibitor Use and the Risk of Small Intestinal Bacterial Overgrowth: A Meta-analysis Clinical Gastroenterology and Hepatology , April 23, 2013

18 Cough Aerosols of Mycobacterium tuberculosis Predict New Infection American Journal of Respiratory and Critical Care Medicine, May 3, 2013

19 Effect of HIV infection on pregnancy-related mortality in sub-Saharan Africa: secondary analyses of pooled community-based data from the network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA) The Lancet, May 17, 2013 Evidence Based Medicine

20 Chagas Disease in Latin American Immigrants With Dilated Cardiomyopathy in New York City Clinical Infectious Diseases, April 18, 2013 Review Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Infectious Disease News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Med Articles

Other Topics in Internal Medicine