Internal Medicine - Infectious Disease News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (67) Full Text Articles (1098) Focus on Thyroid Disease

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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521 Transmission of methicillin-resistant staphylococcus aureus in the long term care facilities in Hong Kong Full Text BMC Infectious Diseases, May 10, 2013 Review Article

522 T cell memory to evolutionarily conserved and shared hemagglutinin epitopes of H1N1 viruses: a pilot scale study Full Text BMC Infectious Diseases, May 10, 2013 Review Article

523 Behavioural and medical predictors of bacterial vaginosis recurrence among female sex workers: longitudinal analysis from a randomized controlled trial Full Text BMC Infectious Diseases, May 10, 2013 Review Article

524 Concentration and High Avidity of Pneumococcal Antibodies Persist at least Four Years after Immunization with Pneumococcal Conjugate Vaccine in Infancy Clinical and Vaccine Immunology, May 10, 2013 Clinical Article

525 Extrapulmonary Infections Caused by a Dominant Strain of Mycobacterium massiliense (Mycobacterium abscessus subspecies bolletii) Clinical Microbiology and Infection, May 10, 2013 Review Article

526 The re-emergence of tuberculosis: what have we learnt from molecular epidemiology Clinical Microbiology and Infection, May 10, 2013 Clinical Guideline Clinical Article

527 Visual detection of human infection with influenza A (H7N9) virus by subtype-specific reverse transcription loop-mediated isothermal amplification with hydroxynaphthol blue dye Clinical Microbiology and Infection, May 10, 2013 Review Article

528 Viral load and humoral immune response in association with disease severity in puumala hantavirus infected patients - implications for treatment Clinical Microbiology and Infection, May 10, 2013 Review Article

529 The relationship between TNF-α gene polymorphism and susceptibility and clearance of the persistent hepatitis B virus infection in a Chinese population: A meta-analysis Clinical Microbiology and Infection, May 10, 2013 Evidence Based Medicine

530 A novel anti-HIV active integrase inhibitor with a favorable in vitro cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase metabolism profile Antiviral Research , May 10, 2013

531 Quantitative Polymerase Chain Reaction Detection of Circulating DNA in Serum for Early Diagnosis of Mucormycosis in Immunocompromised Patients Clinical Infectious Diseases, May 9, 2013 Clinical Article

532 Understanding the Determinants of Antimicrobial Prescribing Within Hospitals: The Role of Prescribing Etiquette Clinical Infectious Diseases, May 9, 2013 Clinical Article

533 A Retrospective Comparative Study of 2-Drug Oral and Intramuscular Cephalosporin Treatment Regimens for Pharyngeal Gonorrhea Clinical Infectious Diseases, May 9, 2013 Clinical Article

534 Breast Milk as a Possible Route of Vertical Transmission of Dengue Virus Clinical Infectious Diseases, May 9, 2013

535 tPA Alu (I/D) Polymorphism Associates With Bacterial Osteomyelitis The Journal of Infectious Diseases, May 9, 2013 Review Article

536 Association of Functional Impairment with Inflammation and Immune Activation in HIV Type 1-Infected Adults Receiving Effective Antiretroviral Therapy The Journal of Infectious Diseases, May 9, 2013 Clinical Article

537 Depression, antidepressant medications, and risk of Clostridium difficile infection Full Text BMC Medicine, May 9, 2013

538 Monitoring Avian Influenza A(H7N9) Virus through National Influenza-like Illness Surveillance, China Full Text Emerging Infectious Diseases, May 9, 2013 Clinical Article

539 Impact of vitamin D insufficiency on insulin homeostasis and beta cell function in nondiabetic male HIV-infected patients HIV Medicine, May 9, 2013 Clinical Article

540 The assessment of risk factors for the Central/East African Genotype of chikungunya virus infections in the state of Kelantan: a case control study in Malaysia Full Text BMC Infectious Diseases, May 9, 2013 Review Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Infective Endocarditis New England Journal of Medicine, April 12, 2013

2 Echocardiography in pericardial diseases: new developments Heart Failure Reviews, April 19, 2013

3 Varicella Zoster Virus-Specific Immune Responses to a Herpes Zoster Vaccine in Elderly Recipients With Major Depression and the Impact of Antidepressant Medications Clinical Infectious Diseases, March 26, 2013

4 Effect of adequate single-drug versus combination antimicrobial therapy on mortality in Pseudomonas aeruginosa bloodstream infections. A post hoc analysis of a prospective cohort Clinical Infectious Diseases, April 17, 2013

5 Antibiotics for brain abscesses in people with cyanotic congenital heart disease Cochrane Reviews, April 3, 2013

6 Update on polymyalgia rheumatica European Journal of Internal Medicine , April 12, 2013

7 Fungal rhinosinusitis: what every allergist should know Clinical & Experimental Allergy, March 27, 2013

8 Infectious Complications Following Transrectal Ultrasound-Guided Prostate Biopsy: New Challenges in the Era of Multidrug-Resistant Escherichia coli Clinical Infectious Diseases, April 18, 2013

9 Interventions to improve professional adherence to guidelines for prevention of device-related infections Cochrane Reviews, April 4, 2013 Evidence Based Medicine

10 Combination Antifungal Therapy for Cryptococcal Meningitis New England Journal of Medicine, April 8, 2013

11 Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies British Medical Journal, April 10, 2013 Free full text

12 Proton Pump Inhibitor Use and the Risk of Small Intestinal Bacterial Overgrowth: A Meta-analysis Clinical Gastroenterology and Hepatology , April 23, 2013

13 Acute pneumonia and the cardiovascular system The Lancet, March 12, 2013 Review Article

14 Carbapenem-resistant Enterobacteriaceae: A menace to our most vulnerable patients Cleveland Clinic Journal of Medicine, April 11, 2013 Free full text

15 Chinese medicinal herbs for influenza Cochrane Reviews, April 11, 2013

16 Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections Cochrane Reviews, March 29, 2013 Review Article

17 Incidence of Campylobacter and Salmonella Infections Following First Prescription for PPI: A Cohort Study Using Routine Data The American Journal of Gastroenterology, April 17, 2013

18 Quadruple therapy for eradication of Helicobacter pylori World Journal of Gastroenterology, February 21, 2013 Free full text

19 Diagnosing tuberculous meningitis ? have we made any progress? Tropical Medicine & International Health, March 27, 2013 Review Article

20 Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: meta-analysis of randomised controlled trials European Journal of Clinical Microbiology & Infectious Diseases, April 10, 2013 Evidence Based Medicine

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Infectious Disease News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine