What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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101 Biomarkers and cytokines of bone turnover: extensive evaluation in a cohort of patients with ankylosing spondylitis Full Text BMC Musculoskeletal Disorders, October 5, 2012
102 Effects of Manidipine and Delapril in Hypertensive Patients With Type 2 Diabetes Mellitus Full Text Hypertension, October 4, 2012 Original Publication Date: October 3, 2011 Clinical Article
103 Six-Month Incidence, Persistence, and Factors Associated With Persistence of Anal Human Papillomavirus in Men: The HPV in Men Study Full Text The Journal of Infectious Diseases, October 4, 2012 Original Publication Date: October 3, 2011
104 Qualitative Analysis of Peer Coaches Experiences with Counseling African Americans About Reducing Heart Disease Risk Full Text Journal of General Internal Medicine, October 4, 2012 Original Publication Date: October 3, 2011
105 Effects of candesartan in hypertensive patients with type 2 diabetes mellitus on inflammatory parameters and their relationship to pulse pressure Full Text Cardiovascular Diabetology, October 4, 2012 Clinical Article
106 The role of mediastinal adipose tissue 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid expression in the development of coronary atherosclerosis in obese patients with ischemic heart disease Full Text Cardiovascular Diabetology, October 4, 2012 Clinical Article
107 Cognitive correlates of repetitive transcranial magnetic stimulation (rTMS) in treatment-resistant depression- a pilot study Full Text BMC Psychiatry, October 4, 2012
108 Recurrent aseptic meningitis in association with Kikuchi-Fujimoto disease: case report and literature review Full Text BMC Neurology, October 4, 2012
109 Evidence of Atrial Functional Mitral Regurgitation Due to Atrial Fibrillation Full Text JACC - Journal of the American College of Cardiology, October 4, 2012 Original Publication Date: October 3, 2011
110 Remission of screen-detected metabolic syndrome and its determinants: an observational study Full Text BMC Public Health, October 4, 2012
111 Efficacy of acupuncture for chronic knee pain: protocol for a randomised controlled trial using a Zelen design Full Text BMC Complementary and Alternative Medicine, October 4, 2012
112 Ten-year trends in HIV prevalence among visitors to public health centers under the National HIV Surveillance System in Korea, 2000 to 2009 Full Text BMC Public Health, October 4, 2012
113 Hospital discharge diagnostic and procedure codes for upper gastro-intestinal cancer: how accurate are they? Full Text BMC Health Services Research, October 4, 2012
114 Association of circulating levels of MMP-8 with mortality from respiratory disease in patients with rheumatoid arthritis Full Text Arthritis Research & Therapy, October 4, 2012
115 Differences in characteristics between healthcare associated and community-acquired infection in community-onset Klebsiella pneumoniae bloodstream infection in Korea Full Text BMC Infectious Diseases, October 4, 2012
116 In-vitro analysis of the microbicidal activity of 6 contact lens care solutions Full Text BMC Infectious Diseases, October 4, 2012
117 Osteomyelitis pubis caused by Kingella kingae in an adult patient: Report of the first case Full Text BMC Infectious Diseases, October 4, 2012
118 Expanded dengue syndrome: subacute thyroiditis and intracerebral hemorrhage Full Text BMC Infectious Diseases, October 4, 2012
119 Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients Full Text Retrovirology, October 4, 2012
120 Erythropoietin, ferritin, haptoglobin, hemoglobin and transferrin receptor in metabolic syndrome: a case control study Full Text Cardiovascular Diabetology, October 4, 2012
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013
2 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text
3
Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association
Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary
4 Advances in Stroke Prevention in Atrial Fibrillation: Enhanced Risk Stratification Combined With the Newer Oral Anticoagulants Clinical Cardiology, April 11, 2013 Free full text Review Article
5 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article
6 The Risk of Taking Ascorbic Acid JAMA Internal Medicine, February 5, 2013
7 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
8 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013
9 Enalapril And Carvedilol for Preventing Chemotherapy-Induced Left Ventricular Systolic Dysfunction in Patients with Malignant Hemopathies. The OVERCOME Trial JACC - Journal of the American College of Cardiology, April 12, 2013
10 Drug Interactions with Grapefruit Juice British Journal of Medical Practitioners, February 12, 2013 Free full text
11 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013
12 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article
13 Infective Endocarditis New England Journal of Medicine, April 12, 2013
14 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013
15 Vitamin D and Calcium Supplementation to Prevent Fractures in Adults: U.S. Preventive Services Task Force Recommendation Statement Annals of Internal Medicine, February 26, 2013 Clinical Guideline
16 Infective Endocarditis New England Journal of Medicine, April 24, 2013 Review Article
17 Osteoporosis treatment European Journal of Internal Medicine , April 24, 2013
18 Bone mineral density testing: Is a T score enough to determine the screening interval? Cleveland Clinic Journal of Medicine, April 3, 2013 Free full text
19 The impact of coffee on health Maturitas, February 26, 2013
20 Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials Cardiovascular Diabetology, April 12, 2013 Free full text
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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