Internal Medicine News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (291) Full Text Articles (9654) Focus on HIV

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

441 The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer Breast Cancer Research and Treatment, June 17, 2013 Clinical Article

442 A retrospective evaluation of chemotherapy dose intensity and supportive care for early-stage breast cancer in a curative setting Breast Cancer Research and Treatment, June 17, 2013 Clinical Article

443 Is a diagnosis of ancillary restless legs syndrome reproducible over time? Experience with the Wayne Hening telephone diagnostic interview Sleep Medicine, June 17, 2013 Clinical Article

444 Distribution and prognosis of molecular breast cancer subtypes defined by immunohistochemical biomarkers in a Spanish population-based study Gynecologic Oncology, June 17, 2013 Clinical Article

445 Selection for replicases in protocells Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

446 Detection of mixed infection from bacterial whole genome sequence data allows assessment of its role in clostridium difficile transmission Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

447 Polymorphisms in the F8 gene and MHC-II variants as risk factors for the development of inhibitory anti-factor VIII antibodies during the treatment of hemophilia A: A computational assessment Full Text PLoS Neglected Tropical Diseases, June 17, 2013

448 STL-based analysis of TRAIL-induced apoptosis challenges the notion of type I/type II cell line classification Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

449 Mass treatment with azithromycin for trachoma: When is one round enough? Results from the PRET trial in the Gambia Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Clinical Article

450 Impact of three rounds of mass drug administration on lymphatic filariasis in areas previously treated for onchocerciasis in Sierra Leone Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Clinical Article

451 A mechanistic understanding of allosteric immune escape pathways in the HIV-1 envelope glycoprotein Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

452 Replacing a native wolbachia with a novel strain results in an increase in endosymbiont load and resistance to dengue virus in a mosquito vector Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

453 Genetic structure and evolution of the leishmania genus in Africa and Eurasia: What does MLSA tell us Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

454 Hybrid equation/agent-based model of ischemia-induced hyperemia and pressure ulcer formation predicts greater propensity to ulcerate in subjects with spinal cord injury Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

455 Improving breast cancer survival analysis through competition-based multidimensional modeling Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Clinical Article

456 The predictive diagnostic value of serial daily bedside ultrasonography for severe dengue in Indonesian adults Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Clinical Article

457 Antimicrobial action of the cyclic peptide bactenecin on burkholderia pseudomallei correlates with efficient membrane permeabilization Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

458 Atmospheric moisture variability and transmission of hemorrhagic fever with renal syndrome in Changsha City, mainland China, 1991-2010 Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

459 Host resistance, population structure and the long-term persistence of bubonic plague: contributions of a modelling approach in the malagasy focus Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

460 Cell patterns emerge from coupled chemical and physical fields with cell proliferation dynamics: The arabidopsis thaliana root as a study system Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Review Article

50 available pages First Previous 23 24 25 26 27 28 29 30 31 32 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

Read the article summary

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

Read the article summary

CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

Read the article summary

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Most Popular Internal Med Articles

Last month's top read Top Articles of 2012

1 Aspirin: Its risks, benefits, and optimal use in preventing cardiovascular events Cleveland Clinic Journal of Medicine, May 8, 2013 Free full text

2 Relationship between 25-Hydroxyvitamin D and All-cause and Cardiovascular Disease Mortality American Journal of Medicine, May 24, 2013 Review Article

3 The effect of topiramate on weight loss in patients with type 2 diabetes Journal of Research in Medical Sciences, May 14, 2013 Evidence Based Medicine

4 The Prevalence and Prognostic Role of Vitamin D Deficiency in Patients with Acute Coronary Syndrome Heart, Lung, and Circulation, April 30, 2013

5 Egg consumption and risk of cardiovascular diseases and diabetes: A meta-analysis Atherosclerosis, May 8, 2013 Evidence Based Medicine Review Article

6 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article

7 An Update on the Cardiovascular Pleiotropic Effects of Milk and Milk Products The Journal of Clinical Hypertension, May 7, 2013 Review Article

8 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

9 Anger and the Heart: Perspectives on Cardiac Risk, Mechanisms and Interventions Progress in Cardiovascular Diseases , May 1, 2013

10 1:1 atrial-flutter. Prevalence and clinical characteristics International Journal of Cardiology, May 2, 2013

11 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

12 New Oral Anticoagulants in Non-Valvular Atrial Fibrillation High Blood Pressure & Cardiovascular Prevention, May 13, 2013

13 Acute myocardial infarction leads to acceleration of atherosclerosis Atherosclerosis, May 1, 2013 Review Article

14 An Anxious Heart: Anxiety and the Onset of Cardiovascular Diseases Progress in Cardiovascular Diseases , May 1, 2013

15 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text

16 Cost-effectiveness of a coronary heart disease secondary prevention program in patients with myocardial infarction: results from a randomised controlled trial BMC Cardiovascular Disorders, May 7, 2013 Free full text

17 Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial The Lancet, May 16, 2013

18 Risk of venous thromboembolism associated with peripherally inserted central catheters: a systematic review and meta-analysis The Lancet, May 20, 2013

19 The Effects of Ezetimibe/Simvastatin versus Simvastatin Monotherapy on Platelet and Inflammatory Biomarkers in Patients with Metabolic Syndrome Cardiology, May 9, 2013

20 Association Between a Hospital's Rate of Cardiac Arrest Incidence and Cardiac Arrest Survival JAMA Internal Medicine, May 21, 2013 Evidence Based Medicine

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Med Articles

Other Topics in Internal Medicine