Internal Medicine News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (257) Full Text Articles (9654) Focus on Angina

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

321 A pilot randomized controlled trial to improve geriatric frailty Full Text BMC Geriatrics, September 26, 2012

322 High glucose mediates endothelial-to-chondrocyte transition in human aortic endothelial cells Full Text Cardiovascular Diabetology, September 26, 2012

323 Effects of weight loss and insulin reduction on arterial stiffness in the save trial Full Text Cardiovascular Diabetology, September 26, 2012

324 Cefditoren: Comparative efficacy with other antimicrobials and risk factors for resistance in clinical isolates causing UTIs in outpatients Full Text BMC Infectious Diseases, September 26, 2012

325 Chancre of the eyelid as manifestation of primary syphilis, and precocious chorioretinitis and uveitis in an HIV-infected patient: a case report Full Text BMC Infectious Diseases, September 26, 2012

326 Differential infection properties of three inducible prophages from an epidemic strain of Pseudomonas aeruginosa Full Text BMC Microbiology, September 26, 2012

327 Molecular epidemiology, antimicrobial susceptibilities and resistance mechanisms of Streptococcus pyogenes isolates resistant to erythromycin and tetracycline in Spain (1994-2006) Full Text BMC Microbiology, September 26, 2012

328 Scale-up of home- based management of malaria based on rapid diagnostic tests and artemisinin based combination therapy in a resource-poor country: results in Senegal Full Text Malaria Journal, September 26, 2012

329 Exploring mediators of accelerometer assessed physical activity in young adolescents in the health in adolescents study -- a group randomized controlled trial Full Text BMC Public Health, September 26, 2012

330 Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation Full Text Retrovirology, September 26, 2012

331 Higher normal ranges of urine albumin-to-creatinine ratio are independently associated with carotid intima-media thickness Full Text Cardiovascular Diabetology, September 26, 2012

332 A pharmacy led program to review anti-psychotic prescribing for people with dementia Full Text BMC Psychiatry, September 26, 2012

333 Executive attention impairment in first-episode schizophrenia Full Text BMC Psychiatry, September 26, 2012

334 Interactions among alcohol dependence, perinatal common mental disorders and violence in couples in rural Vietnam: a cross-sectional study using structural equation modeling Full Text BMC Psychiatry, September 26, 2012

335 The Beijing version of the montreal cognitive assessment as a brief screening tool for mild cognitive impairment: a community-based study Full Text BMC Psychiatry, September 26, 2012

336 Tumor size as measured at initial X-ray examination, not length of bile duct stricture, predicts survival in patients with unresectable pancreatic cancer Full Text BMC Cancer, September 26, 2012

337 A new score predicting the survival of patients with spinal cord compression from myeloma Full Text BMC Cancer, September 26, 2012

338 Stress associated gene expression in blood cells is related to outcome in radiotherapy treated head and neck cancer patients Full Text BMC Cancer, September 26, 2012

339 EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer Full Text Molecular Cancer, September 26, 2012

340 Emergency presentation of the gastric cancer; prognosis and implications for service planning Full Text World Journal of Emergency Surgery, September 26, 2012

483 available pages First Previous 17 18 19 20 21 22 23 24 25 26 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

2 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text

3 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

4 Advances in Stroke Prevention in Atrial Fibrillation: Enhanced Risk Stratification Combined With the Newer Oral Anticoagulants Clinical Cardiology, April 11, 2013 Free full text Review Article

5 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article

6 The Risk of Taking Ascorbic Acid JAMA Internal Medicine, February 5, 2013

7 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013

8 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013

9 Enalapril And Carvedilol for Preventing Chemotherapy-Induced Left Ventricular Systolic Dysfunction in Patients with Malignant Hemopathies. The OVERCOME Trial JACC - Journal of the American College of Cardiology, April 12, 2013

10 Drug Interactions with Grapefruit Juice British Journal of Medical Practitioners, February 12, 2013 Free full text

11 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013

12 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article

13 Infective Endocarditis New England Journal of Medicine, April 12, 2013

14 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013

15 Vitamin D and Calcium Supplementation to Prevent Fractures in Adults: U.S. Preventive Services Task Force Recommendation Statement Annals of Internal Medicine, February 26, 2013 Clinical Guideline

16 Infective Endocarditis New England Journal of Medicine, April 24, 2013 Review Article

17 Osteoporosis treatment European Journal of Internal Medicine , April 24, 2013

18 Bone mineral density testing: Is a T score enough to determine the screening interval? Cleveland Clinic Journal of Medicine, April 3, 2013 Free full text

19 The impact of coffee on health Maturitas, February 26, 2013

20 Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials Cardiovascular Diabetology, April 12, 2013 Free full text

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine