Internal Medicine News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (291) Full Text Articles (9654) Focus on HIV

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

181 Is caspofungin really an effective treatment for Pneumocystis jirovecii pneumonia in immunocompromised patients without human immunodeficiency virus infection? Experiences at a single center and a literature review Scandinavian Journal of Infectious Diseases, June 18, 2013 Review Article

182 Variations of CHROMagar Acinetobacter to detect imipenem-resistant Acinetobacter baumanniicalcoaceticus complex Scandinavian Journal of Infectious Diseases, June 18, 2013 Clinical Article

183 Cutaneous leishmaniasis in a patient receiving infliximab Scandinavian Journal of Infectious Diseases, June 18, 2013 Clinical Article

184 Safety evaluation of laninamivir octanoate hydrate through analysis of adverse events reported during early post-marketing phase vigilance Scandinavian Journal of Infectious Diseases, June 18, 2013 Clinical Article

185 Infectious endocarditis detected by PET/CT in a patient with a prosthetic knee infection: Case report and review of the literature Scandinavian Journal of Infectious Diseases, June 18, 2013 Review Article

186 Anal carcinoma in HIV-infected patients in the period 1995-2009: A Danish nationwide cohort study Scandinavian Journal of Infectious Diseases, June 18, 2013 Clinical Article

187 Lopinavir/ritonavir, atazanavir/ritonavir, and efavirenz in antiretroviral-naive HIV-1-infected individuals over 144 weeks: An open-label randomized controlled trial Scandinavian Journal of Infectious Diseases, June 18, 2013 Clinical Article

188 Factors associated with utilization of preoperative and postoperative rehabilitation services by patients with amputation in the va system: an observational study Physical Therapy, June 18, 2013 Review Article

189 The role of us military physical therapists during recent combat campaigns Physical Therapy, June 18, 2013 Clinical Article

190 Postmilitary adjustment to civilian life: potential risks and protective factors Physical Therapy, June 18, 2013 Clinical Article

191 Clinical reasoning and advanced practice privileges enable physical therapist point-of-care decisions in the military health care system: 3 clinical cases Physical Therapy, June 18, 2013

192 Work reintegration for veterans with mental disorders: a systematic literature review to inform research Physical Therapy, June 18, 2013 Clinical Article

193 Disentangling breast cancer patients perceptions and experiences with regard to endocrine therapy: Nature and relevance for non-adherence The Breast, June 18, 2013 Clinical Article

194 Similar verbal fluency patterns in amnestic mild cognitive impairment and alzheimers disease Archives of Clinical Neurospsychology, June 18, 2013 Clinical Article

195 Fludarabine/2 gy tbi is superior to 2 gy TBI as conditioning for HLA-matched related hct: a phase III randomized trial Biology of Blood and Marrow Transplantation, June 18, 2013 Clinical Article

196 MG132-mediated inhibition of the ubiquitin-proteasome pathway ameliorates cancer cachexia Journal of Cancer Research & Clinical Oncology, June 18, 2013 Clinical Article

197 Long-term outcomes of primary ocular adnexal lymphoma treatment with intraorbital rituximab injections Journal of Cancer Research & Clinical Oncology, June 18, 2013 Clinical Article

198 Phase II study of weekly PM00104 (ZALYPSIS) in patients with pretreated advanced/metastatic endometrial or cervical cancer Medical Oncology, June 18, 2013 Clinical Article

199 Limited impact of prognostic factors in patients with recurrent glioblastoma multiforme treated with a bevacizumab-based regimen Journal of Neuro-Oncology, June 18, 2013 Clinical Article

200 Perfusion and diffusion MRI combined with 11C-methionine PET in the preoperative evaluation of suspected adult low-grade gliomas Journal of Neuro-Oncology, June 18, 2013 Clinical Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Internal Medicine News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Med Articles

Other Topics in Internal Medicine