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Internal Medicine News Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals daily so you can stay current on the latest Internal Medicine news in less that 5 minutes a day! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Latest (384) Full Text Articles (9654) Focus on Neurologic Disorders
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial The Lancet, April 24, 2014    Evidence Based Medicine    Clinical Article

2 Influence of tea consumption on acute myocardial infarction in China population: The INTERHEART China study Angiology, April 24, 2014    Evidence Based Medicine    Clinical Article

3 Door-to-needle times for tissue plasminogen activator administration and clinical outcomes in acute ischemic stroke before and after a quality improvement initiative JAMA, April 24, 2014    Evidence Based Medicine    Clinical Article

4 Pharmacological treatment of Parkinson disease: a review JAMA, April 24, 2014    Review Article    Clinical Article

5 How long do your angiographically normal coronary arteries remain normal? A pilot study Angiology, April 24, 2014    Evidence Based Medicine    Clinical Article

6 Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: The idiopathic intracranial hypertension treatment trial JAMA, April 24, 2014    Evidence Based Medicine    Clinical Article

7 Lorazepam vs diazepam for pediatric status epilepticus: A randomized clinical trial JAMA, April 24, 2014    Evidence Based Medicine    Clinical Article

8 Outcome after conservative management or intervention for unruptured brain arteriovenous malformations JAMA, April 24, 2014    Evidence Based Medicine    Clinical Article

9 Margins for breast-conserving surgery with whole-breast irradiation in stage I and II invasive breast cancer: American Society of Clinical Oncology endorsement of the Society of Surgical Oncology/American Society for Radiation Oncology consensus guideline Journal of Clinical Oncology, April 24, 2014    Review Article

10 Medial vascular calcification revisited: review and perspectives European Heart Journal, April 24, 2014    Review Article

11 The efficacy of ticagrelor is maintained in women with acute coronary syndromes participating in the prospective, randomized, PLATelet inhibition and patient Outcomes (PLATO) trial European Heart Journal, April 24, 2014    Clinical Article

12 Exercise and competitive sports in patients with an implantable cardioverter-defibrillator European Heart Journal, April 24, 2014    Review Article

13 Paradoxical low-flow, low-gradient aortic stenosis despite preserved left ventricular ejection fraction: new insights from weights of operatively excised aortic valves European Heart Journal, April 24, 2014    Clinical Article

14 Management of major bleeding events in patients treated with rivaroxaban vs. warfarin: results from the ROCKET AF trial European Heart Journal, April 24, 2014    Clinical Article

15 The organization, function, and outcomes of ST-elevation myocardial infarction networks worldwide: current state, unmet needs and future directions European Heart Journal, April 24, 2014    Clinical Article

16 Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions The Lancet Infectious Diseases, April 24, 2014    Clinical Article

17 Increased incorporation of antiplasmin into the fibrin network in patients with type 1 diabetes Diabetes Care, April 24, 2014    Clinical Article

18 Weight loss, glycemic control, and cardiovascular disease risk factors in response to differential diet composition in a weight loss program in type 2 diabetes: A randomized controlled trial Diabetes Care, April 24, 2014    Clinical Article

19 Changes in subcutaneous fat cell volume and insulin sensitivity after weight loss Diabetes Care, April 24, 2014    Clinical Article

20 Complement factor 3 is associated with insulin resistance and with incident type 2 diabetes mellitus over a 7-year follow-up period: The CODAM Study Diabetes Care, April 24, 2014    Clinical Article

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Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Med Articles

Last month's top read Top Articles of 2013

1 Is ginger effective for the treatment of irritable bowel syndrome? A double blind randomized controlled pilot trial Complementary Therapies in Medicine, March 4, 2014

2 Tea consumption and leukemia risk: A meta-analysis Tumor Biology, February 12, 2014    Evidence Based Medicine

3 Animal protein intake is associated with higher-level functional capacity in elderly adults: The Ohasama study Journal of the American Geriatrics Society, March 5, 2014

4 Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial The Lancet, March 19, 2014    Evidence Based Medicine

5 Glycated hemoglobin measurement and prediction of cardiovascular disease JAMA, March 26, 2014    Evidence Based Medicine

6 Association of {beta}-blocker therapy with risks of adverse cardiovascular events and deaths in patients with ischemic heart disease undergoing noncardiac surgery: A Danish nationwide cohort study JAMA Internal Medicine, March 11, 2014    Evidence Based Medicine

7 Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: The ADJUST-PE study JAMA, March 20, 2014    Evidence Based Medicine

8 Mortality from ruptured abdominal aortic aneurysms: clinical lessons from a comparison of outcomes in England and the USA The Lancet, March 17, 2014    Evidence Based Medicine

9 Obstructive sleep apnea and risk of cardiovascular events and all-cause mortality: A decade-long historical cohort study PLoS Medicine, February 7, 2014    Free full text    Evidence Based Medicine

10 Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials The Lancet, March 24, 2014    Evidence Based Medicine

11 Multitarget stool DNA testing for colorectal-cancer screening New England Journal of Medicine, March 21, 2014    Evidence Based Medicine

12 Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis The Lancet, October 11, 2013    Evidence Based Medicine

13 Dietary carrot consumption and the risk of prostate cancer European Journal of Nutrition, February 17, 2014

14 Treatment of venous thromboembolism JAMA, February 19, 2014    Evidence Based Medicine

15 Serum levels of fetuin-A, osteoprotegerin and osteopontin in patients with coronary artery disease: Effects of Statin (HMGCoA-Reductase Inhibitor) Therapy Clinical Drug Investigation, March 3, 2014

16 Effects of music on complications during hemodialysis for chronic renal failure patients Hemodialysis International, March 27, 2014

17 Egg consumption and risk of GI neoplasms: dose–response meta-analysis and systematic review European Journal of Nutrition, February 6, 2014    Evidence Based Medicine    Review Article

18 Effect of omega-3 fatty acid supplementation on cancer incidence, non-vascular death, and total mortality: a meta-analysis of randomized controlled trials BMC Public Health, March 5, 2014    Free full text    Evidence Based Medicine

19 Screening for prostate cancer with the prostate-specific antigen test: A review of current evidence JAMA, March 20, 2014    Evidence Based Medicine

20 Effects of spironolactone on long-term mortality and morbidity in patients with heart failure and mild or no symptoms The American Journal of the Medical Sciences, March 25, 2014    Evidence Based Medicine

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicinemore

Other Topics in Internal Medicine

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