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Internal Medicine News Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals daily so you can stay current on the latest Internal Medicine news in less that 5 minutes a day! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Latest (387) Full Text Articles (9654) Focus on Hypertension
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 The prognostic value of Bleeding Academic Research Consortium (BARC) defined bleeding complications in ST-segment elevation myocardial infarction: A Comparison with the Thrombolysis In Myocardial Infarction (TIMI), Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Arteries (GUSTO) and International Society of Thrombosis and Haemostasis (ISTH) bleeding classifications JACC - Journal of the American College of Cardiology, April 21, 2014    Evidence Based Medicine    Clinical Article

2 Use of myocardial strain imaging by echocardiography for the early detection of cardiotoxicity in patients during and after cancer chemotherapy - a systematic review JACC - Journal of the American College of Cardiology, April 21, 2014    Review Article

3 Percutaneous aortic balloon valvotomy in the US: A 13 years perspective American Journal of Medicine, April 21, 2014    Evidence Based Medicine    Clinical Article

4 Dietary fat intake and development of specific breast cancer subtypes Journal of the National Cancer Institute, April 21, 2014    Clinical Article

5 Risk of hospitalised infection in rheumatoid arthritis patients receiving biologics following a previous infection while on treatment with anti-TNF therapy Annals of Rheumatic Diseases, April 21, 2014    Clinical Article

6 Hypoxia and STAT3 signalling interactions regulate pro-inflammatory pathways in rheumatoid arthritis Annals of Rheumatic Diseases, April 21, 2014    Clinical Article

7 Interventions for the treatment of Paget's disease of the vulva Cochrane Reviews, April 21, 2014    Evidence Based Medicine    Clinical Article

8 Factors associated with response to therapy and outcome of patients with primary biliary cirrhosis with features of autoimmune hepatitis Clinical Gastroenterology and Hepatology , April 21, 2014    Continuing Medical Education    Clinical Article

9 Comparative effectiveness of infliximab and adalimumab for Crohn's disease Clinical Gastroenterology and Hepatology , April 21, 2014    Clinical Article

10 The global burden attributable to low bone mineral density Annals of Rheumatic Diseases, April 21, 2014    Review Article

11 Oral anti-pseudomonal antibiotics for cystic fibrosis Cochrane Reviews, April 21, 2014    Evidence Based Medicine    Clinical Article

12 Stents for the prevention of pancreatic fistula following pancreaticoduodenectomy Cochrane Reviews, April 21, 2014    Evidence Based Medicine    Clinical Article

13 Blood pressure targets for hypertension in people with diabetes mellitus Cochrane Reviews, April 21, 2014    Evidence Based Medicine    Clinical Article

14 Prucalopride improves bowel function and colonic transit time in patients with chronic constipation: An integrated analysis The American Journal of Gastroenterology, April 21, 2014    Clinical Article

15 All-cause mortality rate in patients with idiopathic pulmonary fibrosis : implications for the design and execution of clinical trials American Journal of Respiratory and Critical Care Medicine, April 21, 2014    Clinical Article

16 The phosphoinositide-3-kinase isoform PI3Kβ regulates osteoclast-mediated bone resorption Arthritis & Rheumatism, April 21, 2014    Clinical Article

17 Phase i dose-escalation study of 5-day intermittent oral lapatinib therapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer Journal of Clinical Oncology, April 21, 2014    Clinical Article

18 Review of psychodynamic psychotherapy neuroimaging studies Psychotherapy and Psychosomatics, April 21, 2014    Review Article

19 Youth overweight and metabolic disturbances in predicting carotid intima-media thickness, type 2 diabetes, and metabolic syndrome in adulthood: the cardiovascular risk in young finns study Diabetes Care, April 21, 2014    Clinical Article

20 Evolution of abnormal plasma glucagon responses to mixed meal feedings in youth with type 1 diabetes during the first two years after diagnosis Diabetes Care, April 21, 2014    Clinical Article

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Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Med Articles

Last month's top read Top Articles of 2013

1 Is ginger effective for the treatment of irritable bowel syndrome? A double blind randomized controlled pilot trial Complementary Therapies in Medicine, March 4, 2014

2 Tea consumption and leukemia risk: A meta-analysis Tumor Biology, February 12, 2014    Evidence Based Medicine

3 Animal protein intake is associated with higher-level functional capacity in elderly adults: The Ohasama study Journal of the American Geriatrics Society, March 5, 2014

4 Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial The Lancet, March 19, 2014    Evidence Based Medicine

5 Glycated hemoglobin measurement and prediction of cardiovascular disease JAMA, March 26, 2014    Evidence Based Medicine

6 Association of {beta}-blocker therapy with risks of adverse cardiovascular events and deaths in patients with ischemic heart disease undergoing noncardiac surgery: A Danish nationwide cohort study JAMA Internal Medicine, March 11, 2014    Evidence Based Medicine

7 Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: The ADJUST-PE study JAMA, March 20, 2014    Evidence Based Medicine

8 Mortality from ruptured abdominal aortic aneurysms: clinical lessons from a comparison of outcomes in England and the USA The Lancet, March 17, 2014    Evidence Based Medicine

9 Obstructive sleep apnea and risk of cardiovascular events and all-cause mortality: A decade-long historical cohort study PLoS Medicine, February 7, 2014    Free full text    Evidence Based Medicine

10 Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials The Lancet, March 24, 2014    Evidence Based Medicine

11 Multitarget stool DNA testing for colorectal-cancer screening New England Journal of Medicine, March 21, 2014    Evidence Based Medicine

12 Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis The Lancet, October 11, 2013    Evidence Based Medicine

13 Dietary carrot consumption and the risk of prostate cancer European Journal of Nutrition, February 17, 2014

14 Treatment of venous thromboembolism JAMA, February 19, 2014    Evidence Based Medicine

15 Serum levels of fetuin-A, osteoprotegerin and osteopontin in patients with coronary artery disease: Effects of Statin (HMGCoA-Reductase Inhibitor) Therapy Clinical Drug Investigation, March 3, 2014

16 Effects of music on complications during hemodialysis for chronic renal failure patients Hemodialysis International, March 27, 2014

17 Egg consumption and risk of GI neoplasms: dose–response meta-analysis and systematic review European Journal of Nutrition, February 6, 2014    Evidence Based Medicine    Review Article

18 Effect of omega-3 fatty acid supplementation on cancer incidence, non-vascular death, and total mortality: a meta-analysis of randomized controlled trials BMC Public Health, March 5, 2014    Free full text    Evidence Based Medicine

19 Screening for prostate cancer with the prostate-specific antigen test: A review of current evidence JAMA, March 20, 2014    Evidence Based Medicine

20 Effects of spironolactone on long-term mortality and morbidity in patients with heart failure and mild or no symptoms The American Journal of the Medical Sciences, March 25, 2014    Evidence Based Medicine

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicinemore

Other Topics in Internal Medicine

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