Steffen M et al. – Low–quality evidence did not show any statistically significant effect of coffee consumption on BP or the risk of hypertension. Given the quality of the currently available evidence, no recommendation can be made for or against coffee consumption as it relates to BP and hypertension.
- Ovid, MEDLINE (from 1948), EMBASE (from 1988), and all of Web of Science and Scopus.
- RCTs and cohort studies of at least 1–week duration that assessed BP and/or the incidence of hypertension in coffee consumers compared with a control group that consumed less or no coffee.
- Two authors independently reviewed s and full–text articles for inclusion.
- Data were ed using standardized forms.
- Risk of bias in the RCTs was examined using the method described in the Cochrane Handbook for Systematic Reviews of Interventions.
- Quality of the cohort studies were assessed using the Newcastle–Ottawa quality assessment scale for cohort studies.
- Six hundred and ten articles were retrieved and a total of 15 (10 RCTs and five cohort studies) met inclusion criteria.
- Meta–analysis of RCTs demonstrated a pooled weighted difference in mean change in SBP of –0.55 mmHg [95% confidence interval (CI) –2.46 to 1.36) and DBP –0.45 mmHg (95% CI –1.52 to 0.61).
- Meta–analysis of the cohort studies demonstrated a pooled risk ratio for developing hypertension of 1.03 (95% CI 0.98–1.08).