Regional Pulmonary Response to a Methacholine Challenge using Hyperpolarized 3He Magnetic Resonance Imaging
Respirology, 08/31/2012
Costella S et al. – Te authors evaluated the regional pulmonary response to methacholine and salbutamol using 3He magnetic resonance imaging (MRI) and showed heterogeneous ventilation defect percent (VDP) and ADC consistent with bronchoconstriction and gas trapping respectively, post–methacholine challenge (MCh). These regional alterations resolved post–salbutamol.



