Alternative cleavage and polyadenylation during colorectal cancer development
Clinical Cancer Research, 08/09/2012
Morris AR et al. – The results suggest that genes undergoing altered alternative cleavage and polyadenylation (APA) during human cancer progression may be useful novel biomarkers and potentially targeted for disease prevention and treatment. The authors propose that the strategy presented here may be broadly useful in discovery of novel biomarkers for other types of cancer and human disease.