Advances in cell-based therapy for peripheral vascular disease
Blum A et al. – This review considers cell transplantation as a potential treatment for peripheral vascular disease, including ischemic stroke and erectile dysfunction. Bone marrow derived cells are required for endogenous repair in adult individuals affected by angiopathies. Clinical trials using progenitor cells generated from monocytic or non–monocytic cells indicate that both are effective, suggesting that angiogenesis is the result of cross talk between different cells and pathways.