A fluorescence lifetime imaging classification method to investigate the collagen to lipid ratio in fibrous caps of atherosclerotic plaque
Lasers in Surgery and Medicine, 08/21/2012
Phipps JE et al. – Results from this study show that an linear discriminant analysis method of classifying regions of fluorescence lifetime imaging images of carotid plaque into collagen and lipid–rich regions is capable of being automated and used to rate the risk of plaque rupture based on autofluorescence decay dynamics and without the need for fluorescence intensity or contrast agents.



