The role of the mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG in host cell interaction Full Text
BMC Microbiology, 08/10/2012
Kunisch R et al. – MDP1 from M. bovis BCG regulates the growth at acidic pH and the intracellular replication in human monocytes. It furthermore affects cytokine secretion by host cells, and the formation of fused multi–nucleated macrophages. The results suggest an important role of MDP1 in persistent infection.