Lactic acidosis secondary to metformin overdose: a case report Full Text
Journal of Medical Case Reports, 08/03/2012
Timbrell S et al. – The authors provide evidence that the decision to treat severe lactic acidosis in deliberate metformin overdose should not be based on arterial lactate and pH levels, as would be the case in other overdoses. The authors also demonstrate that appropriate treatment with hemodiafiltration and 8.4% sodium bicarbonate, even in patients with a very high lactate and low pH, can be successful.