Induction of Type I IFN Is a Physiological Immune Reaction to Apoptotic Cell-Derived Membrane Microparticles
The Journal of Immunology, 08/08/2012
Schiller M et al. – The authors conclude that induction of plasmacytoid dendritic cells (pDC)–derived IFN–α by Membrane microparticles (MMP) is a physiological event; future investigations are necessary to elucidate whether pDC activation promotes inflammation or propagates tolerance in the context of apoptotic cell clearance.



