Can Activation of Coagulation and Impairment of Fibrinolysis in Patients With Anxiety and Depression Be Reversed After Improvement of Psychiatric Symptoms?: Results of a Pilot Study
The Journal of Nervous and Mental Disease, 08/03/2012
Geiser F et al. – The authors conclude that reduction of severe anxiety and depression may be associated with a reversal of the procoagulant effect (activation of coagulation and impairment of fibrinolysis) of these psychological states.Methods
- Three factors of coagulation and fibrinolysis as well as level of anxiety and depression were reassessed in 12 patients 1 to 3years after intensive inpatient psychotherapy.
- The patients showed a substantial improvement of their severe anxiety disorder and comorbid depressive disorder.
- Simultaneously, the authors found a significant decrease in factor VII and plasminogen activator inhibitor.