Identification and Characterization of Argonaute Protein, Ago2 and Its Associated Small RNAs in Schistosoma japonicum Full Text
PLoS Neglected Tropical Diseases, 08/01/2012
Cai P et al. – In this study, authors identified and characterized one of the three S. japonicum Argonautes, SjAgo2, and its associated small RNAs were found to be predominantly derived from particular classes of retrotransposons. Thus, a major function of SjAgo2 appears to associate with the maintenance of genome stability via suppression of retroelements. The data advance the understanding of the gene regulatory mechanisms in the blood fluke.