Periodic fever as the manifestation of primary Sjogrens syndrome: a case report and literature review
Clinical Rheumatology, 08/03/2012
Wang HC et al. – A 56–year–old male had periodic fever for 5 years and suffered from auditory hallucination and hearing impairment for 3 years. Xerostomia, xerophthalmia, elevated anti–SSA/Ro tilter, positive Schirmer’s test, and lymphocyte infiltrate of mucoserous gland in lip biopsy of this case confirmed the diagnosis of primary Sjogren’s syndrome (pSS). We review literature for fever and neuropsychiatric involvement in pSS case series. Though fever is present in 6–41 % pSS cases, periodic fever has not been reported. Auditory hallucination was rare in cases with pSS. The literature review alerts clinicians that fever and neurological manifestations were not uncommon in pSS cases.