HSV IgG antibody inhibits virus detection in CSF
Journal of Clinical Virology, 08/01/2012
Fening SW et al. – Viral specific IgG is the major determinant of viral inhibition in CSF and prevents virus recovery in cell culture. In CSF from HSE un–infected patients, viral inhibitory IgG originates from circulating serum antibody and is commonly present in CSF. However, this inhibitory IgG is not protective for the development of HSV disease.