Does baseline cerebral blood flow affect task-related blood oxygenation level dependent response in schizophrenia
Schizophrenia Research, 07/16/2012
Liu J et al. – Adjusting for inter–group differences in resting cerebral blood flow (CBF) altered inter–group differences in task–related blood oxygenation level dependent (BOLD) response in some areas, suggesting that assessing resting CBF in task–related BOLD studies could increase sensitivity and validity. In multiple regions, the relationship between resting CBF and task–related signal increases in BOLD differed between patients and controls, providing new evidence of possible metabolic and/or vascular pathology.