Meningococcal minor pilin PilX is responsible for type IV pilus conformational changes associated with signalling to endothelial cells
Infection and Immunity, 07/11/2012
Brissac T et al. – A deletion of a region of PilX exposed on the surface of the fiber had phenotypical consequences identical to that of a PilX deletion. These data support a model in which surface–exposed motifs of PilX use forces generated by pilus retraction to promote conformational changes required for tfp–mediated signalling.