IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the pro-asthmatic response
The American Journal of Physiology - Lung Cellular and Molecular Physiology, 07/17/2012
Josephson MB et al. – The data demonstrate that the pro–asthmatic effects of IL–13 are enabled by impaired endogenous glucocorticoid (GC) activation in the lung that is attributed to upregulation of 11(beta)–HSD2 in the pulmonary epithelium.



