A caveolin-binding domain in the HCN4 channels mediates functional interaction with caveolin proteins
Journal of Molecular and Cellular Cardiology, 07/17/2012
Barbuti A et al. – The conserved CBD present in all HCN isoforms mediates their functional interaction with caveolins. The elucidation of the molecular details of HCN4–cav–1 interaction can provide novel information to understand the basis of cardiac phenotypes associated with some forms of caveolinopathies.