Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease
Thorax, 06/26/2012
Albert P et al. – Post–salbutamol FEV1 change is similar in patients with chronic obstructive pulmonary disease (COPD) and smoking controls but is influenced by baseline lung function and the presence of emphysema. Bronchodilator reversibility status varies temporally and does not distinguish clinically relevant outcomes, making it an unreliable phenotype.
