Lipopolysaccharide induced activin A-follistatin imbalance affects cardiac fibrosis Full Text
Chinese Medical Journal, 06/22/2012
Wen–qi Z et al. – The results suggest that the inflammatory mediator LPS can promote ACT A–FS imbalance in cardiac fibroblasts, mainly overexpression of ACT A. Overexpression of ACT A promotes the proliferation and the secretion of collagens in cardiac fibroblasts through autocrine/paracrine stimulation of NO, and is involved in the pathological process of myocardial fibrosis.



