Prevalence of molecular markers of Plasmodium falciparum drug resistance in Dakar, Senegal Full Text
Malaria Journal, 06/14/2012
Wurtz N et al. – Since 2004, the prevalence of chloroquine resistance had decreased. The prevalence of isolates with high–level pyrimethamine resistance is 83.5%. The prevalence of isolates resistant to sulphadoxine is 40.2%. However, no quintuple mutant (Pfdhfr 108 N, 51I and 59R and Pfdhps 437 G and 540E), which is associated with a high level of sulphadoxine–pyrimethamine resistance, has been identified to date. The resistance to amodiaquine remains moderate.