Expression of genes associated with H factor in fibroblasts infected with Borrelia spirochaetes
Scandinavian Journal of Immunology, 06/14/2012
Geca A et al. – In the result of infection of fibroblast cultivation with a specific Borrelia genospecies, a variable expression of certain CFH and complement system associated genes, specific for one genospecies only: Borrelia afzelii – C1QBP, CD59, C2, CD46 and FHL1; B. garinii – C1S and CLU; Borrelia burgeforii – CFB, A2M and VSIG4, was observed. CFH differentiating infections induced by B. afzelii and B. garinii from infections induced by B. burgdorferii sensu stricto.