Induction of a broad spectrum of inflammation-related genes by Coxsackievirus B3 requires Interleukin-1 signaling
Medical Microbiology and Immunology, 06/08/2012
Rehren F et al. – A broad spectrum of inflammatory cytokines was induced by CVB3 replication via a pathway that requires IL–1 signaling. The results suggest that IL–1ra may be used as a therapeutic agent to limit inflammation and tissue destruction in myocarditis.