Anatomically versus biologically unifocal prostate cancer: a pathological evaluation in the context of focal therapy
Therapeutic Advances in Urology, 05/30/2012
Karavitakis M et al. – Patients with biologically unifocal tumors have better pathological outcome than those with anatomically unifocal disease. At present the assumption that multifocality should a priori exclude patients from any organ–preserving prostate cancer treatment is only theoretical and needs to be validated by future clinical trials since there are a large proportion of patients with multifocal disease apparently suitable for focal prostate therapy.