Internet-based self-management compared with usual care in adolescents with asthma: A randomized controlled trial
Pediatric Pulmonology, 05/30/2012
Rikkers–Mutsaerts ERVM et al. – Internet–based self–management (IBSM) improved asthma–related quality of life and asthma control in adolescents with not well–controlled asthma after 3 months, but not after 12 months.Methods
- Adolescents (12–18 years) with persistent and not well-controlled asthma participated in a randomized controlled trial with 1 year follow-up and were allocated to IBSM (n=46) or usual care (UC, n=44). IBSM consisted of weekly asthma control monitoring with treatment advice by a web-based algorithm.
- Outcomes included asthma-related quality of life (Pediatric Asthma Quality of Life Questionnaire, PAQLQ) and asthma control (Asthma Control Questionnaire, ACQ) and were analyzed by a linear mixed-effects model.
- At 3 months, PAQLQ improved with 0.40 points (95% CI: 0.17-0.62, P<0.01), by IBSM compared to 0.0 points for UC (P=0.02 for the difference).
- At 12 months the between-group difference was -0.05 (95% CI: -0.50 to 0.41, P=0.85).
- At 3 months ACQ improved more in IBSM than in UC (difference: -0.32 points; 95% CI: -0.56 to -0.079, P<0.01).