The early decline in renal function in patients with type 1 diabetes and proteinuria predicts the risk of end-stage renal disease
Kidney International, 05/24/2012
Skupien J et al. – Based on up to 5 years observation, when renal function was within the normal range, the estimates of early estimated glomerular filtration rate (eGFR) slope predicted the risk of end–stage renal disease (ESRD) during subsequent follow–up better than the baseline clinical characteristics of glycated hemoglobin, blood pressure, or the albumin to creatinine ratio. Thus, the early slope of eGFR decline in patients with type 1 diabetes and proteinuria can be used to predict the risk of ESRD.