Diffuse idiopathic skeletal hyperostosis prevalence in subjects affected by severe atherosclerotic cardiovascular diseases
Arthritis Care & Research , 06/04/2012
Zincarelli C et al. - The overall prevalence of DISH was 30.3%. This is expected because of the study population. Obese and older individuals exhibit a higher risk of DISH development.Methods
- Among the 521 consecutive patients admitted to heart diseases rehabilitation program in the Rehabilitative Cardiology Unit, only those (n=436) with a recent coronary artery bypass grafting (CABG), heart valve replacement (HVR) or affected by congestive heart failure (CHF) were enrolled (45 CHR, 338 CABG and 53 HVR).
- All patients underwent a rheumatologic examination, blood sample collections and chest radiographs.
- Body mass index (BMI), blood pressure and information about gender, age, smoking habit and other vascular risk factors were recorded.
- DISH was established according to Resnick and Niwayama criteria.
- In the setting (77.1% male gender) the mean age was 65.44±9.66 years and the overall prevalence of DISH was 30.3%.
- A logistic regression analysis showed that both age (OR:1.076;95%:1.044-1.109;p<0.001), and obesity (OR:2.28;95%:1.33-3.89;p=0.003) resulted significant predictors of the DISH presence.
- Increasing OR for the presence of DISH was found for increasing tertiles of age and of BMI.
- No difference resulted according to other t-VRFs.
- BMI and age directly correlated with CRP levels.