Brain blood-flow change with acute vagus nerve stimulation in treatment-refractory major depressive disorder
Brain Stimulation, 06/12/2012
Conway CR et al. – Regions undergoing regional cerebral blood flow (rCBF) change in response to acute vagus nerve stimulation (VNS) are consistent with the known afferent pathway of the vagus nerve and models of brain network in depression. Larger studies assessing the correlation between acute stimulation patterns and antidepressant outcomes with VNS are needed.