Hepatitis B e antigen (HBeAg) physically associates with receptor-interacting serine/threonine protein kinase-2 and regulates IL-6 gene expression
The Journal of Infectious Diseases, 05/24/2012
Wu S et al. – The findings identified novel molecular mechanisms, whereby HBeAg modulates intracellular signaling pathways by targeting RIPK2, supporting the concept that HBeAg could impair both innate and adaptive immune responses to promote chronic HBV infection.



