Advances in spontaneous intracerebral haemorrhage
International Journal of Clinical Practice, 06/01/2012
Thanvi BR et al. – There are numerous advances in the understanding of the pathogenesis and management, but hardly any change in the overall mortality in the last few decades. There is a poor understanding of the results of surgical trials that has resulted in a large drop in surgical intervention since 2007. Advances in neuroimaging and neurophysiology have improved the understanding of the mechanisms of neuronal injury and existence of perihaematomal `tissue at risk'. Numerous new therapeutic targets have been identified.