Mycobacterium tuberculosis Modulates Macrophage Lipid-Sensing Nuclear Receptors PPAR{gamma} and TR4 for Survival
The Journal of Immunology, 05/21/2012
Mahajan S et al. – Relative mRNA expression levels of these receptors in PBMCs derived from clinical samples convincingly implicate them in tuberculosis susceptibility. These observations expose a novel paradigm in the pathogenesis of M. tuberculosis amenable for pharmacological modulation.



