Incidence and clinical characteristics of myeloproliferative neoplasms displaying a PDGFRB rearrangement
European Journal of Haematology, 05/17/2012
Arefi M et al. – The incidence of patients with PDGFRB rearrangement is low. These patients showed leukocytosis with eosinophilia and anaemia. The efficacy of imatinib therapy in patients showing PDGFRB rearrangement is high. For this reason in all patients with MPN without any other molecular aberration PDGFRB rearrangement should be ascertained.