Oxidative dna damage correlates with cell immortalization and mir-92 expression in hepatocelllular carcinoma Full Text
BMC Cancer, 05/21/2012
Cardin R et al. – The above findings confirm the accumulation in the progression of chronic liver damage to HCC of a ROS–mediated oxidative DNA damage, and suggest that this correlates with induction of telomerase activity and, as a novel finding, with over–expression of miR–92, a microRNA that plays a role in both the apoptotic process and in cellular proliferation pathways.
