Evaluation of Standard- and High-Dose Daptomycin versus Linezolid against Vancomycin-Resistant Enterococcus Isolates in an In Vitro Pharmacokinetic/Pharmacodynamic Model with Simulated Endocardial Vegetations
Antimicrobial Agents and Chemotherapy, 05/17/2012
Hall AD et al. – Daptomycin displayed a dose–dependent response against three VRE isolates, with high–dose daptomycin producing sustained bactericidal activity. Further research is warranted.