Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory

Neurology®, 05/21/2012

Multilocus genotype patterns (MLGPs) provide an alternative analytical approach to predict an individual's genetic risk for episodic memory performance, a surrogate indicator of late–onset Alzheimer disease (LOAD). Identifying genotypic patterns contributing to the decline of an individual's cognitive performance may be a critical step along the road to preclinical detection of Alzheimer disease.

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